EDCTP – PedVacc

(Building Capacity of Infant HIV-1 Vaccine Clinical Trial Centres in Nairobi, Kenya and Fajara, The Gambia)

Funding: CT.2006.33111.002 European and Developing Countries Clinical Trials Partnership (EDCTP)

PI: Tomas Hanke

Time period: 04/01/08-04/06/2012

The long-term goal of this project is to develop a vaccine for prevention of mother-to-child transmission of HIV-1 during breastfeeding.  Includes a phase I/II clinical trial of MVA.HIVA vaccine for infants born to HIV-1/2 uninfected mothers in The Gambia (PV001) and infants born to HIV-1 infected mothers in Kenya (PV002).
Dr. Grace John-Stewart is the PI on this project’s sub-contract to the University of Washington for collaboration on the Kenya site trial: “An open randomized phase I/II study evaluating safety and immunogenicity of a candidate HIV-1 vaccine, MVA.HIVA, administered to healthy infants born to HIV-1 infected mothers.”Study website (restricted access): https://catalysttools.washington.edu/workspace/amblerg/3014/

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