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A simple tool for discovering the hidden biological significance in microarray expression data.



Results for ageing_brain_dn

Results summary View all lists in GO:CellComp View all genes in ageing_brain_dn
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
microtubule associated complex Any multimeric complex connected to a microtubule. 72 0.96 8 8.30 5.76e-06
microtubule cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules. 127 1.70 8 4.71 3.37e-04
cytoplasmic vesicle A vesicle found in the cytoplasm of the cell. 96 1.29 6 4.67 1.91e-03
synaptic vesicle Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane. 26 0.35 3 8.62 4.95e-03
clathrin-coated vesicle A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes. 54 0.72 4 5.53 5.96e-03
proton-transporting two-sector ATPase complex A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F0, V0, A0) and a cytoplasmic compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient. The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archebacterial) enzymes have a similar structure but, under physiological conditions, they pump hydrogen ion rather than synthesize ATP. 33 0.44 3 6.79 9.70e-03

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