Welcome to the L2L Microarray Analysis Tool

A simple tool for discovering the hidden biological significance in microarray expression data.



Results for ageing_brain_dn

Results summary View all lists in L2L MDB View all genes in ageing_brain_dn
List Name Description Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
ageing_brain_dn Age-downregulated in the human frontal cortex 273 3.65 159 43.51 5.34e-220
alzheimers_disease_dn Downregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus 1276 17.08 72 4.22 1.35e-23
microrna_human Predicted human MicroRNA targets 2627 35.17 67 1.91 9.55e-07
alzheimers_incipient_dn Downregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus 180 2.41 12 4.98 6.90e-06
microrna_mammal Predicted MicroRNA targets conserved across human, mouse and rat 1497 20.04 39 1.95 1.00e-04
aged_mouse_hypoth_dn Down-regulated in the hypothalamus of aged (22 months) BALB/c mice, compared to young (2 months) controls 55 0.74 5 6.79 8.57e-04
microrna_vertebrate Predicted MicroRNA targets conserved across human, mouse, rat, zebrafish and fugu 197 2.64 9 3.41 1.49e-03
calres_rhesus_up Upregulated in the vastus lateralis muscle of middle-aged rhesus monkeys subjected to caloric restriction since young adulthood vs. age-matched controls 103 1.38 6 4.35 2.72e-03
ni2_mouse_dn Downregulated by nickel(II) in sensitive A/J mouse lung tissue 48 0.64 4 6.23 3.91e-03
icf_dn Downregulated in B-cells from ICF syndrome (DNMT3B) compared to normals 28 0.37 3 8.00 6.12e-03
hdaci_colon_tsa24hrs_up Upregulated by TSA at 24 hrs in SW260 colon carcinoma cells 31 0.41 3 7.23 8.15e-03

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