Welcome to the L2L Microarray Analysis ToolA simple tool for discovering the hidden biological significance in microarray expression data. |
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| Results summary | View all lists in GO:BiolProc | View all genes in alzheimers_up |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism | The chemical reactions and physical changes involving nucleobases, nucleosides, nucleotides and nucleic acids. | 2499 | 267.58 | 336 | 1.26 | 1.05e-05 |
| transcription | The synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 1634 | 174.96 | 225 | 1.29 | 6.50e-05 |
| transcription, DNA-dependent | The synthesis of RNA on a template of DNA. | 1577 | 168.85 | 215 | 1.27 | 1.62e-04 |
| regulation of transcription | Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. | 1562 | 167.25 | 213 | 1.27 | 1.71e-04 |
| regulation of biological process | Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. | 2645 | 283.21 | 342 | 1.21 | 1.77e-04 |
| regulation of transcription, DNA-dependent | Any process that modulates the frequency, rate or extent of DNA-dependent transcription. | 1525 | 163.29 | 208 | 1.27 | 1.99e-04 |
| regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism | Any process that modulates the frequency, rate or extent of the chemical reactions and physical changes involving nucleobases, nucleosides, nucleotides and nucleic acids. | 1583 | 169.50 | 215 | 1.27 | 2.00e-04 |
| cell proliferation | The multiplication or reproduction of cells, resulting in the rapid expansion of a cell population. | 1245 | 133.31 | 171 | 1.28 | 4.91e-04 |
| regulation of metabolism | Any process that modulates the frequency, rate or extent of chemical reactions and physical changes involving a substance. | 1703 | 182.35 | 226 | 1.24 | 5.10e-04 |
| regulation of cellular process | Any process that modulates the frequency, rate or extent of cellular processes, those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. | 899 | 96.26 | 127 | 1.32 | 8.38e-04 |
| cell-matrix adhesion | The binding of a cell to the extracellular matrix via adhesion molecules. | 83 | 8.89 | 19 | 2.14 | 1.06e-03 |
| protein amino acid phosphorylation | The process of introducing a phosphoric group on to a protein. | 599 | 64.14 | 88 | 1.37 | 1.54e-03 |
| DNA metabolism | The chemical reactions and physical changes involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. | 491 | 52.57 | 74 | 1.41 | 1.75e-03 |
| positive regulation of I-kappaB kinase/NF-kappaB cascade | Any process that activates or increases the rate of an I-kappaB kinase/NF-kappaB induced cascade. | 87 | 9.32 | 19 | 2.04 | 1.91e-03 |
| epidermal growth factor receptor signaling pathway | The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands. | 23 | 2.46 | 8 | 3.25 | 1.92e-03 |
| cell cycle | The sequence of events by which a cell duplicates its contents and divides in two; comprises, at a minimum, replication and segregation of DNA; during the course of a cell cycle the cell usually also doubles its mass and duplicates all cytoplasmic organelles. | 847 | 90.69 | 118 | 1.30 | 2.00e-03 |
| I-kappaB kinase/NF-kappaB cascade | A series of reactions initiated by the activation of the transcription factor NF-kappaB. NF-kappaB is sequestered by the inhibitor I-kappaB, and is released when I-kappaB is phosphorylated by activated I-kappaB kinase. | 115 | 12.31 | 23 | 1.87 | 2.35e-03 |
| establishment and/or maintenance of chromatin architecture | 143 | 15.31 | 27 | 1.76 | 2.50e-03 | |
| positive regulation of signal transduction | Any process that activates or increases the rate of signal transduction. | 89 | 9.53 | 19 | 1.99 | 2.51e-03 |
| DNA packaging | 153 | 16.38 | 28 | 1.71 | 3.36e-03 | |
| regulation of cell proliferation | Any process that modulates the frequency, rate or extent of cell proliferation. | 355 | 38.01 | 55 | 1.45 | 3.48e-03 |
| regulation of cell cycle | Any process that modulates the frequency, rate or extent of the cell cycle. | 522 | 55.89 | 76 | 1.36 | 3.81e-03 |
| complement activation, classical pathway | Processes involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes. | 37 | 3.96 | 10 | 2.52 | 4.52e-03 |
| cell differentiation | The process whereby relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. | 237 | 25.38 | 39 | 1.54 | 4.53e-03 |
| female gamete generation | The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. | 16 | 1.71 | 6 | 3.50 | 4.65e-03 |
| regulation of physiological process | Any process that modulates the frequency, rate or extent of a physiological process, a processes specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. | 1801 | 192.84 | 228 | 1.18 | 4.85e-03 |
| base-excision repair | In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. | 12 | 1.28 | 5 | 3.89 | 5.83e-03 |
| protein kinase cascade | A series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. | 288 | 30.84 | 45 | 1.46 | 6.50e-03 |
| mRNA metabolism | The chemical reactions and physical changes involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. | 199 | 21.31 | 33 | 1.55 | 7.53e-03 |
| response to bacteria | A change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the perception of bacteria. | 29 | 3.11 | 8 | 2.58 | 9.38e-03 |
| RNA processing | Any process involved in the conversion of a primary RNA transcript into a mature RNA molecule. | 279 | 29.87 | 43 | 1.44 | 9.66e-03 |
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