Welcome to the L2L Microarray Analysis ToolA simple tool for discovering the hidden biological significance in microarray expression data. |
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| Results summary | View all lists in GO:MoleFunc | View all genes in alzheimers_up |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| transition metal ion binding | Interacting selectively with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver. | 803 | 85.98 | 124 | 1.44 | 2.41e-05 |
| zinc ion binding | Interacting selectively with zinc (Zn) ions. | 649 | 69.49 | 103 | 1.48 | 3.72e-05 |
| nucleic acid binding | Interacting selectively with any nucleic acid. | 2356 | 252.26 | 314 | 1.24 | 3.80e-05 |
| specific RNA polymerase II transcription factor activity | Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II. | 37 | 3.96 | 12 | 3.03 | 3.19e-04 |
| DNA binding | Interacting selectively with DNA (deoxyribonucleic acid). | 1691 | 181.06 | 225 | 1.24 | 4.55e-04 |
| hyaluronic acid binding | Interacting selectively with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. | 16 | 1.71 | 7 | 4.09 | 7.66e-04 |
| transcription regulator activity | Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor. | 1200 | 128.49 | 164 | 1.28 | 7.80e-04 |
| RNA polymerase II transcription factor activity | Functions to initiate or regulate RNA polymerase II transcription. | 249 | 26.66 | 43 | 1.61 | 1.17e-03 |
| histone deacetylase activity | Catalysis of the hydrolysis of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes. | 6 | 0.64 | 4 | 6.23 | 1.65e-03 |
| cell adhesion receptor activity | OBSOLETE. Combining with cell adhesion molecules to initiate a change in cell activity. | 44 | 4.71 | 12 | 2.55 | 1.79e-03 |
| collagen binding | Interacting selectively with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). | 19 | 2.03 | 7 | 3.44 | 2.53e-03 |
| metal ion binding | Interacting selectively with any metal ion. | 1518 | 162.54 | 197 | 1.21 | 2.98e-03 |
| protein kinase activity | Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate. | 554 | 59.32 | 79 | 1.33 | 5.50e-03 |
| cysteine-type endopeptidase activity | Catalysis of the hydrolysis of nonterminal peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center. | 109 | 11.67 | 21 | 1.80 | 5.57e-03 |
| deacetylase activity | Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule. | 12 | 1.28 | 5 | 3.89 | 5.83e-03 |
| cysteine-type peptidase activity | Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides; a cysteine residue is at the active center. | 117 | 12.53 | 22 | 1.76 | 6.22e-03 |
| DNA N-glycosylase activity | Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site. | 8 | 0.86 | 4 | 4.67 | 6.44e-03 |
| binding | The selective and stoichiometric interaction of a molecule with one or more specific sites on another molecule. | 6563 | 702.72 | 765 | 1.09 | 7.33e-03 |
| transcription factor activity | Any protein required to initiate or regulate transcription; includes both gene regulatory proteins as well as the general transcription factors. | 878 | 94.01 | 117 | 1.24 | 8.42e-03 |
| phosphotransferase activity, alcohol group as acceptor | Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). | 631 | 67.56 | 87 | 1.29 | 9.03e-03 |
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