Welcome to the L2L Microarray Analysis ToolA simple tool for discovering the hidden biological significance in microarray expression data. |
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| Results summary | View all lists in L2L MDB | View all genes in incip_alz_dn |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| alzheimers_incipient_dn | Downregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus | 306 | 2.77 | 158 | 57.09 | 1.71e-233 |
| alzheimers_disease_dn | Downregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus | 2123 | 19.20 | 159 | 8.28 | 1.77e-89 |
| oldwerner_dn | Commonly downregulated in fibroblasts from Werner Syndrome and old individuals, compared to young | 270 | 2.44 | 11 | 4.50 | 4.42e-05 |
| ageing_brain_dn | Age-downregulated in the human frontal cortex | 229 | 2.07 | 10 | 4.83 | 5.46e-05 |
| p53_brca1_up | Upregulated by expression of p53 in p53-null, brca1-null MEFs; most genes are further upregulated by simultaneous expression of BRCA1 | 44 | 0.40 | 3 | 7.54 | 7.43e-03 |
| h2o2_csbrescued_up | Upregulated by H2O2 in CSB-rescued fibroblasts (Table 1) | 133 | 1.20 | 5 | 4.16 | 7.49e-03 |
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