Welcome to the L2L Microarray Analysis ToolA simple tool for discovering the hidden biological significance in microarray expression data. |
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| Results summary | View all lists in GO:MoleFunc | View all genes in ageing_hs3_dn |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| binding | The selective and stoichiometric interaction of a molecule with one or more specific sites on another molecule. | 5329 | 1.61 | 8 | 4.96 | 2.72e-04 |
| hormone activity | Any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects. | 91 | 0.03 | 2 | 72.68 | 3.68e-04 |
| calmodulin binding | Interacting selectively with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. | 107 | 0.03 | 2 | 61.81 | 5.08e-04 |
| kinesin binding | Interacting selectively and stoichiometrically with kinesin, a cytoplasmic protein responsible for moving vesicles and organelles towards the distal end of microtubules. | 5 | 0.00 | 1 | 661.42 | 1.51e-03 |
| molecular_function | Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions. | 8634 | 2.61 | 9 | 3.45 | 1.53e-03 |
| catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | 2820 | 0.85 | 5 | 5.86 | 1.86e-03 |
| ATPase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction. | 212 | 0.06 | 2 | 31.20 | 1.96e-03 |
| ATP binding | Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | 808 | 0.24 | 3 | 12.28 | 2.02e-03 |
| adenyl nucleotide binding | Interacting selectively with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate. | 822 | 0.25 | 3 | 12.07 | 2.12e-03 |
| calcium-transporting ATPase activity | Catalysis of the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). | 8 | 0.00 | 1 | 413.39 | 2.42e-03 |
| calcium ion transporter activity | Enables the directed movement of calcium (Ca) ions into, out of, within or between cells. | 10 | 0.00 | 1 | 330.71 | 3.02e-03 |
| signal transducer activity | Mediates the transfer of a signal from the outside to the inside of a cell by means other than the introduction of the signal molecule itself into the cell. | 2017 | 0.61 | 4 | 6.56 | 3.55e-03 |
| purine nucleotide binding | Interacting selectively with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate. | 1013 | 0.31 | 3 | 9.79 | 3.80e-03 |
| nucleotide binding | Interacting selectively with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety. | 1024 | 0.31 | 3 | 9.69 | 3.92e-03 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. | 355 | 0.11 | 2 | 18.63 | 5.35e-03 |
| microtubule binding | Interacting selectively with microtubules, filaments composed of tubulin monomers. | 19 | 0.01 | 1 | 174.06 | 5.73e-03 |
| neuropeptide hormone activity | 20 | 0.01 | 1 | 165.35 | 6.03e-03 | |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. | 1218 | 0.37 | 3 | 8.15 | 6.32e-03 |
| GABA-A receptor activity | Combining with the neurotransmitter GABA-A (gamma aminobutyric acid) to initiate a change in cell activity. | 22 | 0.01 | 1 | 150.32 | 6.63e-03 |
| calcium-dependent protein serine/threonine phosphatase activity | Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. | 23 | 0.01 | 1 | 143.79 | 6.93e-03 |
| GABA receptor activity | Combining with the neurotransmitter GABA (gamma aminobutyric acid) to initiate a change in cell activity. | 24 | 0.01 | 1 | 137.80 | 7.23e-03 |
| di-, tri-valent inorganic cation transporter activity | Enables the directed movement of inorganic cations with a valency of two or three into, out of, within or between cells. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage. | 26 | 0.01 | 1 | 127.20 | 7.83e-03 |
| receptor binding | Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. | 471 | 0.14 | 2 | 14.04 | 9.21e-03 |
| calcium ion binding | Interacting selectively with calcium ions (Ca2+). | 472 | 0.14 | 2 | 14.01 | 9.25e-03 |
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