Welcome to the L2L Microarray Analysis ToolA simple tool for discovering the hidden biological significance in microarray expression data. |
|||
| Results summary | View all lists in L2L MDB | View all genes in ageing_hs3_up |
| List Name | Description | Total probes |
Expected matches |
Actual matches |
Fold Enrichment |
Binomial p-value |
|---|---|---|---|---|---|---|
| ageing_brain_up | Age-upregulated in the human frontal cortex | 253 | 0.26 | 33 | 126.87 | 5.23e-58 |
| alzheimers_incipient_up | Upregulated in correlation with incipient Alzheimer's Disease, in the CA1 region of the hippocampus | 347 | 0.36 | 33 | 92.50 | 2.96e-53 |
| alzheimers_disease_up | Upregulated in correlation with overt Alzheimer's Disease, in the CA1 region of the hippocampus | 1472 | 1.51 | 33 | 21.81 | 1.66e-32 |
| diab_neph_dn | Downregulated in the glomeruli of cadaver kidneys from patients with diabetic nephropathy, compared to normal controls | 420 | 0.43 | 10 | 23.16 | 3.80e-11 |
| microrna_human | Predicted human MicroRNA targets | 2621 | 2.69 | 16 | 5.94 | 2.87e-08 |
| microrna_mammal | Predicted MicroRNA targets conserved across human, mouse and rat | 1441 | 1.48 | 11 | 7.43 | 4.76e-07 |
| rcc_nl_up | Upregulated in VHL-rescued renal carcinoma vs. normal renal cells (Fig. 2) | 223 | 0.23 | 4 | 17.45 | 9.36e-05 |
| atria_up | Upregulated in the atria of healthy hearts, compared to venticles | 254 | 0.26 | 4 | 15.32 | 1.54e-04 |
| dac_panc_up | Upregulated by DAC treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells | 378 | 0.39 | 4 | 10.29 | 6.89e-04 |
| brca1_up | Upregulated by induction of BRCA1 in EcR-293 cells | 40 | 0.04 | 2 | 48.63 | 8.03e-04 |
| dac_panc50_up | 50 "most interesting" genes upregulated by DAC treatment in at least one of four pancreatic cancer cell lines, but not in normal (HPDE) cells | 50 | 0.05 | 2 | 38.91 | 1.25e-03 |
| htert_up | Upregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls | 58 | 0.06 | 2 | 33.54 | 1.68e-03 |
| htert_dn | Downregulated in hTERT-immortalized fibroblasts vs. non-immortalized controls | 59 | 0.06 | 2 | 32.97 | 1.74e-03 |
| cmv_dn | Downregulated by infection of fibroblasts with CMV | 80 | 0.08 | 2 | 24.32 | 3.17e-03 |
| shh_dn | Downregulated by sonic hedgehog (shh) expression in murine neuronal precursor cells | 4 | 0.00 | 1 | 243.17 | 4.11e-03 |
| ifn_beta_up | Upregulated by treatment with IFN-beta | 93 | 0.10 | 2 | 20.92 | 4.25e-03 |
| vegf_hmmec_up | Up-regulated at any time-point (3hrs, 6hrs, or 12hrs) follwing VEGF treatment of human myometrial microvascular endothelial cells | 98 | 0.10 | 2 | 19.85 | 4.71e-03 |
| werneronly_up | Upregulated in fibroblasts from Werner (but not old) individuals, compared to young | 5 | 0.01 | 1 | 194.54 | 5.13e-03 |
| brca_er_neg | Genes whose expression is consistently negatively correlated with estrogen receptor status in breast cancer - higher expression is associated with ER-negative tumors | 769 | 0.79 | 4 | 5.06 | 8.68e-03 |
Printer-friendly version of this page