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A simple tool for discovering the hidden biological significance in microarray expression data.



Results for diab_neph_up

Results summary View all lists in L2L MDB View all genes in diab_neph_up
List Name Notes Total
probes
Expected
matches
Actual
matches
Fold
Enrichment
Binomial
p-value
hdaci_colon_but12hrs_dn Downregulated by butyrate at 12 hrs in SW260 colon carcinoma cells 191 1.56 11 7.05 6.47e-07
calres_mouse_neocortex_dn Downregulated in the neocortex of aged (30-month) mice subjected to caloric restriction since young adulthood vs. age-matched controls 71 0.58 6 10.35 2.70e-05
hdaci_colon_allbut_dn Downregulated by butyrate at any timepoint in SW260 colon carcinoma cells 350 2.86 11 3.85 1.79e-04
oxstress_breastca_up Upregulated by H2O2, Menadione and t-BH in breast cancer cells 71 0.58 5 8.62 3.02e-04
ageing_brain_up Age-upregulated in the human frontal cortex 393 3.21 11 3.43 4.74e-04
vegf_hmmec_up Up-regulated at any time-point (3hrs, 6hrs, or 12hrs) follwing VEGF treatment of human myometrial microvascular endothelial cells 126 1.03 6 5.83 6.34e-04
brca1_dn Downregulated by induction of BRCA1 in EcR-293 cells 22 0.18 3 16.70 7.47e-04
adip_vs_fibro_dn Downregulated following 7-day differentiation of murine 3T3-L1 fibroblasts into adipocytes 51 0.42 4 9.60 8.18e-04
egf_hdmec_up Up-regulated in human dermal (foreskin) microvascular endothelial cells that were stimulated to proliferate with prolonged EGF treatment, versus non-stimulated quiescent controls. 96 0.78 5 6.38 1.20e-03
cmv_dn Downregulated by infection of fibroblasts with CMV 144 1.18 6 5.10 1.27e-03
adip_vs_preadip_dn Downregulated in mature murine adipocytes (7 day differentiation) vs. preadipocytes (6 hr differentiation) 65 0.53 4 7.54 2.03e-03
hdaci_compilation_up Compilation of upregulated genes from all HDAC-inhibitor-related lists 474 3.87 11 2.84 2.11e-03
elongina_ko_up Upregulated in MES cells from elongin-A knockout mice 163 1.33 6 4.51 2.37e-03
tzd_adip_up Upregulated by treatment of mature murine adipocytes with the PPARgamma agonist troglitazone 10 0.08 2 24.49 2.87e-03
ros_mouse_aorta_dn Down-regulated in mouse aorta by chronic treatment with PPARgamma agonist rosiglitazone 73 0.60 4 6.71 3.09e-03
hdaci_colon_alltsa_up Upregulated by TSA at any timepoint in SW260 colon carcinoma cells 232 1.89 7 3.69 3.23e-03
hdaci_colon_tsa12hrs_up Upregulated by TSA at 12 hrs in SW260 colon carcinoma cells 40 0.33 3 9.18 4.29e-03
hdaci_colon_but24hrs_dn Downregulated by butyrate at 24 hrs in SW260 colon carcinoma cells 313 2.56 8 3.13 4.64e-03
hdaci_colon_but48hrs_dn Downregulated by butyrate at 48 hrs in SW260 colon carcinoma cells 326 2.66 8 3.00 5.88e-03
ni2_mouse_dn Downregulated by nickel(II) in sensitive A/J mouse lung tissue 48 0.39 3 7.65 7.16e-03
parp_ko_up Upregulated in MEF cells from PARP knockout mice 49 0.40 3 7.50 7.58e-03

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