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Clinical Coagulation Division

The Clinical Coagulation Division is involved in clinical testing, research and teaching related to bleeding and thrombotic disorders.

Clinical Coagulation Faculty

Diagnostic Testing

A comprehensive set of clinical tests are available for the diagnosis and monitoring of bleeding and thrombotic disorders.

  • Routine coagulation tests (PT, PTT, TT, fibrinogen, d-dimer)
  • Factor activity assays (II, V, VII, VIII, IX, X, XI, XII)
  • Factor inhibitor assays
  • Von Willebrand factor assays (vWF Ag, Multimers, RIPA)
  • Platelet aggregation studies (collagen, ADP, arachidonic acid, risocetin)
  • Lupus Inhibitor assay (Hexagonal phase phospholipid, DRVVT)
  • Thrombophilia assays (protein C, protein S, antithrombin)
  • Activated Protein C Resistance/Factor V DNA screening
  • Fibrinolysis assays (t-PA activity and antigen, PAI-1 activity and antigen)


Current projects include:

  • Regulation of fibrinolytic activity in blood.
  • New assays for the detection of hemostatic and thrombotic abnormalities.
  • Effect of cardiopulmonary bypass on the coagulation and fibrinolytic systems.


The Clinical Coagulation Division participates in training programs for undergraduate medical laboratory science students, medical students, clinical pathology residents and hematopathology fellows. In addition, a Master of Science degree is offered in Laboratory Medicine with concentration in the Clinical Coagulation area. Please see Education section for more information.



Last updated: 6/22/00