Hematopathology Laboratory

Morphologic Evaluation

It is extremely important to combine information obtained from our special studies with morphologic examination of the tissue used for diagnosis. For this reason we request H & E sections or Wright-stained smears of specimens sent for immunologic or molecular diagnostic studies. In addition, cytological examination is performed on cells obtained from various body fluids.

Cytological Examination of Body Fluids
A cytocentrifuge is used to concentrate cells from CSF and other body fluids so that the cytology of those cells may be evaluated using a Wright-Giemsa stain. This test is available 24 hours a day, Monday through Sunday. The director of the laboratory reviews each slide preparation for malignant hematopoietic or non-hematopoietic cells, and the findings are reported by computer printout.

Specimen requirements: Any body fluid

Sézary Cell Preparation
Sézary cells are peripheralized malignant T cells seen in some patients with mycosis fungoides. Peripheral blood smears are stained with Wright-Giemsa stain and evaluated by the director of the laboratory for the presence of Sézary cells. The laboratory director will issue a written report containing a quantitation of Sézary cells and an interpretation.

Specimen requirements: One 5 ml tube EDTA-anticoagulated (lavender top) peripheral blood

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Last updated: 6/22/00