| REAL Classification (ref. 4) |
Working Formulation Equivalent(s) |
| Precursor B-lymphoblastic leukemia/lymphoma |
Lymphoblastic |
| B-cell chronic lymphocytic leukemia/prolymphocytic leukemia/small
lymphocytic lymphoma |
Small lymphocytic |
| Lymphoplasmacytoid lymphoma |
Small lymphocytic with plasmacytoid differentiation |
| Mantle cell lymphoma |
Diffuse small cleaved cell or small lymphocytic |
| Follicle center lymphoma, follicular, predominantly small
cell (grade I) |
Follicular small cleaved cell |
| Follicle center lymphoma, follicular, mixed (grade II) |
Follicular mixed small cleaved and large cell |
| Follicle center lymphoma, follicular, predominantly large
cell (grade III) |
Follicular large cell |
| Follicle center lymphoma, diffuse (predominantly small cell) |
Diffuse small cleaved cell |
| Marginal zone B-cell lymphoma |
|
| Extranodal: low grade B-cell lymphoma of MALT type |
Small lymphocytic |
| Nodal |
Small lymphocytic |
| Splenic marginal zone lymphoma with or without villous lymphocytes |
Small lymphocytic, diffuse small cleaved cell |
| Hairy cell leukemia |
None |
| Plasmacytoma/plasma cell myeloma |
Extramedullary plasmacytoma |
| Diffuse large B-cell lymphoma |
Diffuse large cell/immunoblastic |
| Primary mediastinal large B-cell lymphoma |
Diffuse large cell/immunoblastic |
| Burkitt's lymphoma |
Small noncleaved cell, Burkitt's |
| High grade B-cell lymphoma, Burkitt-like |
Small noncleaved cell non-Burkitt's |
| Precursor T-lymphoblastic lymphoma/leukemia |
Lymphoblastic |
| T-cell chronic lymphocytic leukemia |
Small lymphocytic |
| T-cell/NK-cell large granular lymphocyte leukemia |
Small lymphocytic, diffuse small cleaved cell |
| Mycosis fungoides/Sézary syndrome |
Mycosis fungoides |
| Peripheral T-cell lymphoma |
Diffuse small cleaved cell, diffuse mixed small and large
cell, diffuse large cell, large cell immunoblastic |
| Angioimmunoblastic T-cell lymphoma |
Diffuse mixed small and large cell, large cell immunoblastic |
| Angiocentric lymphoma |
Diffuse small cleaved cell, diffuse mixed small and large
cell, diffuse large cell, large cell immunoblastic |
| Intestinal T-cell lymphoma |
Diffuse small cleaved cell, diffuse mixed small and large
cell, diffuse large cell, large cell immunoblastic |
| Adult T-cell lymphoma/leukemia |
Diffuse small cleaved cell, diffuse mixed small and large
cell, diffuse large cell, large cell immunoblastic |
| Anaplastic large cell (CD30+) lymphoma |
Large cell immunoblastic |
