Genetics and Solid Tumor Diagnostic Testing
New
BRCA1 and BRCA2 added to BROCA Cancer Risk Panel
In response to the Supreme Court's decision in the case of Association For Molecular Pathology et al. v. Myriad Genetics, Inc., et al., the Department of Laboratory Medicine at the University of Washington Medical Center will provide clinical testing for mutations in the BRCA1 and BRCA2 genes as part of the BROCA Cancer Risk Panel effective June 14, 2013.
Testing is performed with next-generation sequencing technology, which detects all classes of disease-causing mutations. The Department's clinical test is based on the research of Drs. Tom Walsh and Mary-Claire King, who first developed this technology to study hereditary risk of breast and ovarian cancer and reported it in 2010.
For more information on testing»
UW-OncoPlex™ Cancer Gene Panel
UW-OncoPlex™ is a multiplexed gene sequencing panel that detects mutations in tumor tissue in 194 cancer-related genes for cancer treatment, prognosis, and diagnosis.
For more information including how to order and pricing»
Featured at SCCA»
The clinical laboratory offers DNA-based testing for a variety of disorders. For further information on testing, please consult the following links:
- Test List with CPT codes - revised 01/11/2013
- ALK Fusion FISH
- Alpha-Thalassemia
- Alpha–Hemoglobin DNA Sequence
- Beta–Hemoglobin DNA Sequence
- BRAF Mutations
- BROCA – Cancer Risk Panel (July 2012)
- ColoSeq™ – Lynch and PolyPosis Panel
- ColoSeq™ – Polyposis Panel
- ColoSeq™/BROCA - Single Gene Testing NEW
- Cystic Fibrosis
- Deafness/Hearing Loss (connexin 26 & 30)
- DNA Storage Prior to Testing
- EGFR Mutations
- Factor V Leiden
- Fragile X Syndrome and fragile X-related FXTAS and POI
- Hemochromatosis
- Huntington Disease
- IDH Mutations
- KIT Mutations NEW
- KRAS Mutation Analysis
- Maternal Cell Contamination
- Microsatellite Instability (DNA Test)
- Mitochondrial DNA Mutation Panel
- Myotonic Dystrophy 1
- Prothrombin 20210A
- Spinal and Bulbar Muscular Atrophy
- Spinocerebellar Ataxia Types 1, 2, 3, 6, and 7
- UW-OncoPlex™ Tumor Test NEW
Test Requisition
- Genetics Requisition [pdf] updated 5/30/13
Specimen requirements:
- Blood: 5 ml with EDTA anticoagulant (purple top tube)
- Tissue: see individual test requirements
- Prenatal or other sample types: contact laboratory
BROCA and ColoSeq™ Forms
- Pre-Authorization form updated 5/30/2013
- Points to Consider, patient information NEW
Contact information:
- Attention: Genetics Lab
- Clinical lab, Room NW220
- University of Washington Medical Center
- 1959 NE Pacific Street
- Seattle, WA 98195
- Lab Tel: (206) 598-6429 M-F (7:30 AM - 4:00 PM)
- Lab Fax: (206) 598-0304
- Supervisor: Deborah Barden, Ph.D. (206) 598-6429 barden@uw.edu
- Supervisor: Robert Livingston, Ph.D. (206) 598-6429 bobl@uw.edu
- Genetic Counselor: Angela Jacobson, M.S., L.G.C. (206) 598-1149 agibson@uw.edu
- Faculty: Colin C. Pritchard M.D., Ph.D. (206) 598-8400
- Faculty: Brian H. Shirts, M.D., Ph.D. (206) 598-0557
- Faculty: Karen Stephens, Ph.D., FACMG (206) 598-0096
- Faculty: Jonathan F. Tait, M.D., Ph.D. (206) 598-6131
Laboratory Accreditation and Licensure:
- College of American Pathologists (CAP No. 2463701) [pdf* expires 9/5/2013]
- CLIA ID Number 50D0631935 [pdf* expires 6/30/2013]
updated 6/14/2013
*Software capable of displaying a PDF is required for viewing or printing this document. Adobe Reader is available free of charge from the Adobe website at http://www.adobe.com/products/acrobat/readstep2.html