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HomeFaculty › Lawrence Corey, MD

Lawrence Corey, MD

photo Dr. Lawrence Corey

Professor, Departments of Medicine and Laboratory Medicine;
President and Director, Fred Hutchinson Cancer Research Center

Contact Information

Fred Hutchinson Cancer Research Center
D1-060
1100 Fairview Ave N, LE-500
Seattle, WA 98109
Tel: 206.667.6770
Fax: 206.667.7711
Email: lcorey@uw.edu

Personal Biography

Dr. Corey pioneered the development of antiviral therapy for human chronic viral infections. He is a world renowned virologist who has worked in a wide variety of areas including diagnostic virology, antiviral therapy, vaccine development and viral immunology. He has led an HSV research program that has been continuously funded by the NIH since 1978. He is currently President and Director of the Fred Hutchinson Cancer Research Center and the PI of the NIH supported HIV Vaccine Trials Network: an international collaboration of investigators devoted to developing a globally effective HIV vaccine. Besides work, Larry is an avid tennis player, occasional skier, and fan of early morning exercise. He is a devoted grandfather to four granddaughters.

Education and Training

  • BS with high distinction, University of Michigan, Ann Arbor, MI, 1967
  • MD, University of Michigan Medical School, Ann Arbor, MI, 1971
  • University of Michigan Medical Center Hospitals, Ann Arbor, Intern, 1971-72
  • University of Michigan Medical Center Hospitals, Junior Assistant Resident, 1972-73
  • Epidemic Intelligence Service Officer, Respiratory and Special Pathogens Branch, Viral Diseases Division, Centers for Disease Control, Atlanta, GA, 1973-75
  • Senior Fellow, Division of Infectious Disease, University of Washington, Seattle, WA, 1975-77

Clinical Interests

  • Virology

Research Interests

  • Herpesvirus immunobiology
  • Infections in the immunocompromised host, especially those undergoing bone marrow transplant
  • HIV vaccine development

Current Research

  • NIH/NIAID U01 AI 068614-05 (L. Corey, PI), 6/29/2006-5/31/2013, $21,223,150 Leadership Group for a Global HIV Vaccine Trials Network
  • NIH R01 AI-42528-15 (L. Corey, PI) 12/01/97-03/31/12 $250,618; Renewal: 4/01/12-3/31/17, $453,463 (FY) Cytotoxic T Cell Response to HSV in HIV Infected Persons
  • NIH/NCI, P30 CA-15704-36 (L. Corey, PI), 1/01/77-12/31/2013, $6,3331,387 Cancer Center Support Grant
  • NIH/NCI, HHSN2612000004C / ADB# N02CO-2010-00004 (L. Corey; Co-PI: Thompson), 12/1/09-11/30/14, $28974,004 Cancer Information Service

Selected Publications

  1. Janes H, Frahm N, DeCamp A, Rolland M, Gabriel E, Wolfson J, Hertz T, Kallas E, Goepfert P, Friedrich DP, Corey L, Mullins JI, McElrath MJ, Gilbert P. MRKAd5 HIV-1 Gag/Pol/Nef vaccine-induced T-cell responses inadequately predict distance of breakthrough HIV-1 sequences to the vaccine or viral load. PLoS One. 2012;7(8):e43396.
    [PubMed]
  2. Duerr A, Huang Y, Buchbinder S, Coombs RW, Sanchez J, del Rio C, Casapia M, Santiago S, Gilbert P, Corey L, Robertson MN for the Step/ HVTN 504 study team. Extended follow-up of participants in a recombinant adenovirus HIV vaccine trial (Step study) suggests that the increased risk of HIV acquisition among vaccines wanes over time. J Infect Dis. 2012 Jul;206(2):258-266.
    [PubMed]
  3. Peng T, Zhu J, Phasouk K, Koelle D, Wald A and Corey L. An effector phenotype of CD8+ T cells at the junction epithelieum during clinical quiescence of HSV-2 infection. J Virol. 2012 Oct;86(19):10587-96.
    [PubMed]
  4. Green ML, Leisenring W, Wtachel D, Pergam SA, Sandmaier BM, Wald A, Corey L, Boeckh M. Efficacy of a viral load-based, risk-adaptive, preemptive treatment strategy for prevention of Cytomegalovirus disease after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2012 Nov; 18(11):1687-99.
    [PubMed]
  5. Lu Y, Celum C, Wald A Baeten JM, Cowan F, Delany-Moretlwe S, Reid SE, Hughes JP, Wilcox E, Corey L, Hendrix CW. Acyclovir achieves lower concentration in African HIV-seronegative, HSV-2 seropositive women compared to non-African populations. Antimicrob Agents Chemother. 2012 May;56(5):2777-9.
    [PubMed]

Honors and Awards

  • Phi Beta Kappa, University of Michigan, 1967 Phi Kappa Phi, University of Michigan, 1967
  • University of Michigan Regent's Alumni Award, 1965-19
  • Teaching commendation, University of Washington Medical School Senior Class, 1982, 1984
  • Special Service Award, National Reyes Syndrome Foundation, 1983
  • Achievement Award, American Venereal Disease Association, 1984
  • Special Service Award, National Institutes Allergy and Infectious Diseases, 1992
  • Richard Clemmons Lecturer, University of Alabama, 1995
  • Thomas Parran Lifetime Achievement Award, American STD Association, 1997
  • Pan American Society Clinical Virology Award, 1998
  • Distinguished Alumnus Award, University of Michigan Medical School, 1999
  • Lifetime Achievement Award for Patient Education and Advocacy, American Social Health Association, 2001
  • John D. Enders Memorial Lectureship, Infectious Diseases Society of America, 2001
  • Wesley Spink Memorial Lectureship, "Developing an HIV Vaccine", University of Minnesota, 2001 (Renewal, 2006)
  • MERIT Award, Cytotoxic T Cell Reservoirs to HSV among HIV Infected Persons, 2001
  • Institute for Scientific Information, Member "Highly Cited Researcher", 2002-present
  • Louis Weinstein Lectureship, Tufts University, 2002
  • Children's Hospital of Pennsylvania, Annual Silver Lectureship on Children, Adolescents and Families Affected by HIV Disease, 2004
  • Top 20 funded scientists in the United States 2005 (no. 6) Scientist Magazine, 2006
  • Best Doctors in America, 2005-2006
  • Western Association of Physicians, Distinguished Lecture, 2007
  • Thomas Merigan Lectureship, Stanford University, 2007
  • Jonathan Lax Memorial Lecture, Wistar Institute, HIV Vaccine Development Post STEP, 2008
  • Elected, Institute of Medicine, National Academy of Sciences, 2008
  • Lifelong AIDS Alliance "Ned Behnke Leadership Award", 2011
  • Elected, Member, American Academy of Arts and Sciences, 2012
  • Cubist-ICAAC Award, American Society for Microbiology, 2012

 

Last updated: 1/15/2013

HomeFaculty › Lawrence Corey, MD

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