Kerstin Edlefsen, MD
Assistant Professor;
Associate Director, Hematopathology Division
Assistant Director, UWMC Bone Marrow Service
Contact Information
University of Washington
Department of Laboratory Medicine
Seattle Cancer Care Alliance Mail Stop G7-800
825 Eastlake Ave. E.
Seattle, WA 98109
Tel: 206.288.7042
Fax: 206.288.7127
Email: edlefsen@uw.edu
Personal Biography
Dr. Edlefsen is a Seattle native, who lives in Wallingford with her husband and two children. She is a pathologist with expertise in hematopathology. She enjoys bringing diverse diagnostic modalities to the diagnosis and monitoring of leukemia and lymphoma, and collaborating with clinical colleagues to provide state-of-the-art cancer care.
Education and Training
- Hematopathology Fellow, University of Washington School of Medicine, Seattle, WA, 2008-2009
- Surgical Pathology Fellow/Co-Chief Resident, Anatomic Pathology, University of Washington School of Medicine, Seattle, WA, 2006-2007
- Resident in Pathology and Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, 2002-2006
- MD, University of Washington School of Medicine, Seattle, WA, 2002
- BA/BS, The Evergreen State College, Olympia, WA, 1997
Clinical Interests
- Hematopathology
- Morphologic diagnosis of leukemia and lymphoma
- Flow Cytometry
- Non-neoplastic disorders of bone marrow and lymph nodes
Research Interests
- Lymphomagenesis
- Epidemiology of leukemia and lymphoma
- Preneoplastic conditions in leukemia/lymphoma including monoclonal B-cell lymphocytosis
- Aging and immune function
Current Research
Dr. Edlefsen's primary research interests lie in understanding the pathogenesis of mature B cell neoplasms. She is particularly interested in understanding the relationship between clonal lymphocyte expansions and the development of lymphoma, with an emphasis on chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma. Specific research endeavors include:
- Exploring the relationship between serum markers of chronic immune dysregulation and prospective risk of B cell lymphoma
- Flow cytometric detection of epidemiologically significant B and T lymphocyte subsets and their relationship to health and aging in elderly women
- Relationship between monoclonal B cell lymphocytosis (MBL), markers of immune function, peripheral blood counts, and other factors in elderly women
Selected Publications
- De Roos AJ, Mirick D, Edlefsen KL, LaCroix AZ, Kopecky KJ, Madeleine MM, Magpantay L, Martinez-Maza O. Markers of B-Cell Activation in Relation to Non-Hodgkin Lymphoma. Cancer Research, 2012 Sep 15; 72(18):4733-43.
[PubMed] - Linden M, Gopal A, and Edlefsen KL. Case report: Acute appendicitis in a man undergoing therapy for mantle cell lymphoma. Case Report Hematol. 2012;2012:868151 doi: 10.1155/2012/868151.
[PubMed] - Edlefsen KL, Greisman HA, Yi HS, Mantei KM, Fromm JR. Early lymph node involvement by mantle cell lymphoma limited to the germinal center: Report of a case with a novel 'follicular in-situ' growth pattern. Am J Clin Pathol. 2011 Aug; 136(2):276-281.
[PubMed] - Edlefsen KL, Jackson RD, Prentice RL, Janssen I, Rajkovic A, O'Sullivan MJ, Anderson G. The effects of postmenopausal hormone therapy on serum estrogen, progesterone, and sex hormone-binding globulin levels in healthy postmenopausal women. Menopause 2010; 17(33):622-629.
[PubMed] - Edlefsen KL, Tait JF, Wener MH, Astion M. Utilization and Diagnostic Yield of Neurogenetice Testing at a Tertiary Care Facility. Clinical Chemistry 2007;53(6): 1016-22.
[PubMed]
Honors and Awards
- Strandjord-Clayson Award, University of Washington Department of Laboratory Medicine, 2006
- Alpha Omega Alpha, 2002
Last updated: 1/22/2013