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HomeFaculty › Kerstin Edlefsen, MD

Kerstin Edlefsen, MD

photo Dr. Kerstin Edlefsen, MD

Assistant Professor;
Associate Director, Hematopathology Division
Assistant Director, UWMC Bone Marrow Service

Contact Information

University of Washington
Department of Laboratory Medicine
Seattle Cancer Care Alliance Mail Stop G7-800
825 Eastlake Ave. E.
Seattle, WA 98109
Tel: 206.288.7042
Fax: 206.288.7127

Personal Biography

Dr. Edlefsen is a Seattle native, who lives in Wallingford with her husband and two children. She is a pathologist with expertise in hematopathology. She enjoys bringing diverse diagnostic modalities to the diagnosis and monitoring of leukemia and lymphoma, and collaborating with clinical colleagues to provide state-of-the-art cancer care.

Education and Training

  • Hematopathology Fellow, University of Washington School of Medicine, Seattle, WA, 2008-2009
  • Surgical Pathology Fellow/Co-Chief Resident, Anatomic Pathology, University of Washington School of Medicine, Seattle, WA, 2006-2007
  • Resident in Pathology and Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, 2002-2006
  • MD, University of Washington School of Medicine, Seattle, WA, 2002
  • BA/BS, The Evergreen State College, Olympia, WA, 1997

Clinical Interests

  • Hematopathology
  • Morphologic diagnosis of leukemia and lymphoma
  • Flow Cytometry
  • Non-neoplastic disorders of bone marrow and lymph nodes

Research Interests

  • Lymphomagenesis
  • Epidemiology of leukemia and lymphoma
  • Preneoplastic conditions in leukemia/lymphoma including monoclonal B-cell lymphocytosis
  • Aging and immune function

Current Research

Dr. Edlefsen's primary research interests lie in understanding the pathogenesis of mature B cell neoplasms. She is particularly interested in understanding the relationship between clonal lymphocyte expansions and the development of lymphoma, with an emphasis on chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and mantle cell lymphoma. Specific research endeavors include:

  • Exploring the relationship between serum markers of chronic immune dysregulation and prospective risk of B cell lymphoma
  • Flow cytometric detection of epidemiologically significant B and T lymphocyte subsets and their relationship to health and aging in elderly women
  • Relationship between monoclonal B cell lymphocytosis (MBL), markers of immune function, peripheral blood counts, and other factors in elderly women

Selected Publications

  1. Edlefsen KL, Martínez-Maza O, Madeleine MM, Magpantay L, Mirick DK, Kopecky KJ, Lacroix AZ, De Roos AJ. Cytokines in Serum in Relation to Future Non-Hodgkin Lymphoma Risk: Evidence for associations by histologic subtype. Int J Cancer. 2014 Aug 15;135(4):913-22.

  2. De Roos AJ, Martinez-Maza O, Jerome KR, Mirick DK, Kopecky KJ, Madeleine MM, Magpantay L, Edlefsen KL, Lacroix AZ. Investigation of Epstein-Barr Virus as a Potential Cause of B-Cell Non-Hodgkin Lymphoma in a Prospective Cohort. Cancer Epidemiol Biomarkers Prev. 2013 Oct;22(10):1747-55.

  3. De Roos AJ, Mirick D, Edlefsen KL, LaCroix AZ, Kopecky KJ, Madeleine MM, Magpantay L, Martínez-Maza O. Markers of B-Cell Activation in Relation to Non-Hodgkin Lymphoma. Cancer Research,;2012 Sep 15;72(18):4733-43.

  4. Kabat GC, Kim MY, Wactawski-Wende J, Bea JW, Edlefsen KL, Adams-Campbell LL, De Roos AJ, Rohan TE.  Anthropometric factors, physical activity, and risk of Non-Hodgkins lymphoma in the Women's Health Initiative. Cancer Epidemiol. 2012 Feb;36(1):52-9.

  5. Linden M, Gopal A, and Edlefsen KL. Case report: Acute appendicitis in a man undergoing therapy for mantle cell lymphoma. Case Report Hematol. 2012;2012:868151 doi: 10.1155/2012/868151.
  6. Edlefsen KL, Greisman HA, Yi HS, Mantei KM, Fromm JR. Early lymph node involvement by mantle cell lymphoma limited to the germinal center: Report of a case with a novel ‘follicular in-situ’ growth pattern. Am J Clin Pathol. 2011 Aug;136(2):276-281.

Honors and Awards

  • Strandjord-Clayson Award, University of Washington Department of Laboratory Medicine, 2006
  • Alpha Omega Alpha, 2002

Last updated: 2/17/2015

HomeFaculty › Kerstin Edlefsen, MD

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