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HomeFaculty › Shalini Pereira, MS, PhD

Shalini Pereira, MS, PhD

photo Dr. Shalini Pereirat

Assistant Professor;
Scientific Director, Clinical Immunogenetics Laboratory, SCCA;
Assistant Member, Clinical Research Division, FHCRC

Contact Information

University of Washington
Department of Laboratory Medicine, NW120
Box 357110
1959 Pacific St.
Seattle, WA 98195-7110
Email: spereira@seattlecca.org

Personal Biography

Dr. Pereira enjoys reading, baking, traveling and spending time with family.

Education and Training

  • BS Microbiology and Biochemistry, Bombay University, India, 1987
  • MS Biochemistry, Bombay University, India, 1989
  • MS Biochemistry, University of Rochester Medical Center, Rochester, New York, 1991
  • PhD Biochemistry, University of Rochester Medical Center, Rochester, New York, 1996

Clinical Interests

  • HLA typing of patients, family members, and potential related and unrelated or cord blood donors prior to allogeneic hematopoietic stem cell transplant (HSCT).
  • Evaluation of patient alloimmune status, antibody sensitization and resultant donor compatibility prior to HSCT.
  • Post-transplant Chimerism testing of patients after HSCT (and for certain specific protocols before transplant) to determine recipient/donor origin of nucleated hematopoietic cells.

Research Interests

  • Studying anti-HLA antibodies and their role in stem cell transplantation
  • The use of desensitization protocols to reduce or eliminate high risk antibodies
  • Evaluating new bio-markers for Graft versus Host disease

Current Research

Dr. Pereira's research is aimed at developing tools to evaluate micro-chimerism and to provide surveillance for post transplant relapse/minimal residual disease.

Selected Publications

  1. Mack SJ, Cano P, Hollenbach JA, He J, Hurley CK, Middleton D, Moraes ME, Pereira SE, et al (2012) Common and Well-Documented HLA Alleles: 2012 Update to the CWD Catalogue. Tissue Antigens. 2013 Apr;81(4):194-203. doi: 10.1111/tan.12093.
    [PubMed]
  2. McGoldrick SM, Bleakley ME, Guerrero A, Turtle CJ, Yamamoto TN, Pereira SE, Delaney CS, Riddell SR. (2012) Cytomegalovirus-specific T cells are primed early after cord blood transpant but fail to expand and control virus in vivo. Blood. 2013 Apr 4;121(14):2796-803. doi: 10.1182/blood-2012-09-453720. Epub 2013 Feb 14.
    [PubMed]
  3. O'Donnell, P.V., Harrington, E., Gooley, T.A., Pagel, J.M., Pereira, S., Flowers, M.E., Hansen, J.A., Burroughs, L.M., Sandmaier, B.M., Storb, R.F., Luznik, L., Jones, R.J., Symonds, H.J., Kasamon, Y.L. and Fuchs, E. (2012) Cyclophosphamide-induced tolerance following hematopoietic cell transplantation from haploidentical donors. Hematologica. In Press.
  4. Newell, LF, Milano, F, Nicoud, IB, Pereira, S, Gooley, TA, Heimfeld, S, Delaney, C. (2012) Early CD3 Peripheral Blood Chimerism Predicts the Long-Term Engrafting Unit Following Myeloablative Doube-Cord Blood Transplantation. Biol Blood Marrow Transplant. 2012 Aug;18(8):1243-9. Epub 2012 Feb 8.
    [PubMed]
  5. O'Brien KL, Pereira SE, Wagner J, Shadman M, Hendrie P, Nelson K, Gernsheimer TB, Price T, Reyes JD, Nester T. Transfusion-associated graft-versus-host disease in a liver transplant recipient: an unusual presentation and review of the literature. Transfusion. 2013 Jan;53(1):174-80.
    [PubMed]

Honors and Awards

  • University of Rochester, Dept of Biochem Graduate Fellowship, 1989-1996
  • NIH Post-Doctoral Fellowship, Project Grant, 1996-1997
  • California Cancer Research Program, Post-Doctoral Fellowship, 2000-2002
  • McCormick Travel Grant Award, 2007

Last updated: 5/1/2013

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