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HomeFaculty › Morayma Reyes, MD, PhD

Morayma Reyes, MD, PhD

photo Dr. Morayma Reyes

Assistant Professor;
Director, Coagulation Laboratory, UWMC and HMC

Contact Information

University of Washington
Department of Laboratory Medicine, NW120
Box 358050
850 Republican Street, Room 432
Seattle, WA 98109-8050
Tel: 206.598.6180
Email: morayma@uw.edu

Personal Biography

Dr. Reyes is originally from Puerto Rico and maintains Puerto Rican tradition such as salsa dancing, cooking Puerto Rican food and enjoys Puerto Rican music and literature. Dr Reyes likes skiing, painting and reading.

Education and Training

  • BS (Magna Cum Laude) University of Puerto Rico, 1996
  • PhD University of Minnesota, Dept. of Microbiology, Immunology, and Cancer Biology, 2001
  • MD University of Minnesota, 2003
  • Clinical Pathology Residency, University of Washington, Seattle, WA 2003-2006
  • Postdoctoral Fellow, Department of Neurology, University of Washington, Seattle, WA, 2003-2006

Clinical Interests

  • Coagulation

Research Interests

  • Stem cells
  • Cardiovascular biology
  • Muscular dystrophy

Current Research

  • American Heart Association: 7/1/2011 to 6/30/2013, "The good and the bad: elucidating the role of Sca-1+ perivascular cells in the pathogenesis of fibrosis of the heart". In muscular dystrophy models, fibrosis of the heart is localized in the perivascular tissue surrounding coronary arteries and arterioles. We propose to study the role of Sca-1 perivascular cells in the pathogenesis of fibrosis. Principal Investigator.
  • RaceMD: 9-1-2011 to 9-30-2012, "Sphingosine based therapy for muscular dystrophy". In this program we are conducting pre-clinical trials in mouse models of muscular dystrophy to evaluate the efficacy of S1P based therapies to ameliorate muscular dystrophy. Co-PI.
  • Tietze Award: 10-1-12 to 9-30-2012, "Characterization of salivary gland cancer stem cells" The existence of a cancer stem cell (CSC) has been demonstrated for certain leukemias, germ line tissues and a number of solid tumors. Although a putative salivary gland cancer stem cell is yet to be discovered, the heterogenous nature of salivary gland tumors indicate that they may originate from a primitive cell line capable of generating all the lineages characteristic of the salivary gland tumor. Despite the wide spread focus on CSCs in other tissues, very little progress has been made toward detecting and characterizing CSCs in human salivary gland tumors. This proposal aims to demonstrate that CSCs occur in mucoepidermoid carcinoma (MEC) of salivary glands, and to characterize their gene expression profiles in order to begin developing basic knowledge of CSCs in various salivary gland tumors.

Selected Publications

  1. Ieronimakis N, Hays A, Reyes M. Bone marrow-derived cells do not engraft into skeletal muscle microvasculature but promote angiogenesis after acute injury. Exp Hematol. 2012;40(3):238-249.e3.
    [PubMed]
  2. Press JZ, Reyes M, Pitteri SJ, Pennil C, Garcia R, Goff BA, Hanash SM, Swisher EM. Microparticles From Ovarian Carcinoma Are Shed Into Ascites and Promote Cell Migration. Int J Gynecol Cancer. 2012 May;22(4):546-52.
    [PubMed]
  3. Janebodin K, Reyes M. Neural crest-derived Dental Pulp Stem Cells function as ectomesenchyme to support salivary gland tissue formation. Dentistry. 2012;2(2):S13.
    [omicsonline.org]
  4. Reesukumal K, Pratumvinit B, Janebodin K, Reyes M. Characterization of cardiac Sca-1+ cells from heart. JSCRT. 2011(S1-002): S1-002.
  5. Janebodin K, Reesukumal K, Pratumvinit B, Ieronimakis N, Balasundaram G, Reyes M. Isolation and Characterization of Neural Crest-Derived Stem Cells from Dental pulp of Neonatal Mice. PLOs One. 6(11):e27526, 2011.
    [PubMed]

Honors and Awards

  • Tietze Award, $25,000, 2012 Cambridge Who's Who Member-Executives and Professionals, 2010
  • Princeton Global Networks Honors, 2009
  • Madison Who's Who Member-Executives and Professionals, 2008
  • Jain Foundation Award for greatest contribution in scientific forum, $1000. 2007
  • Perkins Coie Award, Best Pilot Research Junior Faculty, $20,000. 2007
  • Marian E. Smith award, Junior Faculty Award, $25,000. 2006
  • Paul E. Strandjord Young Investigator Award, ACLPS, 2006
  • Travel Award for Postdoctoral Trainees, FASEB summer conference, 2005 Strandjord-Clayson award for best research, 2004
  • Travel Award for Trainees, ASH Meeting, 2003
  • Travel Award for Trainees, ISEH Meeting, 2002
  • Travel Award for Trainees, ASCI/APP Joint, 2002
  • J. Jacob Kaplan, Minnesota Medical Foundation, Best Scientific Cardiology Research, 2002
  • Nelson Goldberg Scholarship, Best Published Scientific Article by an M.D./PhD Student, 2001
  • Best Scientific Poster in Medicine, Medicine Department, 2000 Highest scored abstract by a PhD student, ASH Merit Award, 1999
  • Best student in Chemistry, Universityof Puerto Rico, 1996 Best organic chemistry abstract by an undergraduate student, American Chemical Society Meeting, 1995

Last updated: 1/22/2013

HomeFaculty › Morayma Reyes, MD, PhD

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