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HomeFaculty › Mark Wener, MD

Mark Wener, MD

photo Dr. Mark Wener

Professor, Department of Laboratory Medicine;
Adjunct Professor, Department of Medicine;
Service Chief, University of Washington Medical Center Clinical Laboratories;
Director, Immunology Division, Laboratory Medicine;
Attending Physician, Rheumatology

Contact Information

University of Washington
Department of Laboratory Medicine, NW120
Box 357110
1959 Pacific St.
Seattle, WA 98195-7110
Tel: 206.598.6152
Fax: 206.598.6189

Personal Biography

A Chicagoan by birth, Mark lived in the Midwest until moving to Seattle for a research fellowship to study lupus immune complex disease. His research helped define the role of autoantibodies to the collagen-like region of C1q in lupus, and its relation to other autoantibodies associated with lupus nephritis. He is currently involved in developing dried blood spot assays used by epidemiologists and other investigators. His clinical work as a rheumatologist includes work with clinical investigators at the Fred Hutchinson Cancer Research Center in transplantation of scleroderma patients

Education and Training

  • B.A. Chemistry, University of Chicago, Chicago, IL, June 1970
  • M.D., Washington University, St. Louis, MO, May 1974
  • Residency, Internal Medicine, University of Iowa Hospital, Iowa City, IA, June 1974-76
  • Residency, Internal Medicine, University of Iowa Hospital, Iowa City, IA, July 1977-78
  • Fellowship, Agricultural Medicine, Saku Hospital, Usuda, Japan;
    Sponsor: University of Iowa Department of Agricultural Medicine and Rural Health, Sept-Dec 1976
  • Fellowship, Rheumatology, University of Iowa Hospital, Iowa City, IA, June 1978-80
  • Fellowship, Rheumatology & Immunology Research, Rheumatology Division, University of Washington, Seattle, WA, July 1980-81

Clinical Interests

  • Rheumatology

Research Interests

  • Development of autoimmune lab tests
  • Development of dried blood spot assays
  • Infections
  • Faculty development and mentoring metrics

Current Research

  • Development of multiplexed dried blood spot assays for epidemiologic surveys
  • Inflammatory markers in epidemiologic studies
  • Ultrasound to assess scleroderma skin
  • Development of test panels for autoimmune rheumatic diseases

Selected Publications

  1. Toriola AT, Cheng TY, Neuhouser ML, Wener MH, Zheng Y, Brown E, Miller JW, Song X, Beresford SA, Gunter MJ, Caudill MA, Ulrich CM. Biomarkers of inflammation are associated with colorectal cancer risk in women but are not suitable as early detection markers. Int J Cancer. 2012 Nov 15. doi: 10.1002/ijc.27942. [Epub ahead of print] PubMed PMID: 23161620.
  2. Imayama I, Ulrich CM, Alfano CM, Wang C, Xiao L, Wener MH, Campbell KL, Duggan C, Foster-Schubert KE, Kong A, Mason CE, Wang CY, Blackburn GL, Bain CE, Thompson HJ, McTiernan A. Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial. Cancer Res. 2012 May 1;72(9):2314-26. PubMed PMID: 22549948; PubMed Central PMCID: PMC3342840.
  3. Wener MH. Multiplex, megaplex, index and complex: the present and future of laboratory diagnostics in rheumatology. Arthritis Res Ther. 2011 Nov 24;13(6):134. PubMed PMID: 22129036.
  4. Williams L, Ulrich CM, Larson T, Wener MH, Wood B, Chen-Levy Z, Campbell PT, Potter J, McTiernan A, De Roos AJ. Fine Particulate Matter (PM2·5) Air Pollution and Immune Status Among Women in the Seattle Area. Arch Environ Occup Health. 2011 Jul-Sep;66(3):155-65. PubMed PMID: 21864104.
  5. Dillon SR, Harder B, Lewis KB, Moore MD, Liu H, Bukowski TR, Hamacher NB, Lantry MM, Maurer M, Krejsa CM, Ellsworth JL, Pederson S, Elkon KB, Wener MH, Dall'era M, Gross JA. B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimer's are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin. Arthritis Res Ther; 2010; 12(2):R48. PMID: 20302641.

Honors and Awards

  • Bronfenbrenner Prize, Washington University, 1971
  • Alpha Omega Alpha, 1974 o Lange Medical Award, Washington University, 1974
  • Arthritis Foundation Fellowship, 1981-83
  • "Best Doctors in America: Pacific Region", 1996
  • America's Top Doctors, Rheumatology (Castle-Connolly), 2001-11

Last updated: 1/30/2013

HomeFaculty › Mark Wener, MD

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