Department of Laboratory Medicine
University of Washington
 
Clinical assay interference and limitations


Antithrombin III [AT3]

Method: Stago Chromogenic Antithrombin Assay

Patients on hirudin (Refludan) and argatroban (Novastan) may show interference due to the direct thrombin inhibition. This may cause an over-estimation of the antithrombin concentration. Patients on heparin therapy may see decreased antithrombin concentrations.

Reference: Stago Technical Bulletin, June 21, 2001.




















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