Department of Laboratory Medicine
University of Washington
Clinical assay interference and limitations
Coagulation Factor Assays [F2, F5, F7, F8, F9, F10, F11, F12]
Methodology: Stago STA Clottable Factor assays
Patients on hirudin (Refludan) and argatroban (Novastan) may show prolonged clotting times due to the direct thrombin inhibition. This may cause an under-estimation of the factor concentrations.
Reference: Stago Technical Bulletin, June
21, 2001.
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