Department of Laboratory Medicine
University of Washington
 
Clinical assay interference and limitations

Platelet Function Screen Test [PLFS]

Methodology: Dade Platelet Function Analyzer

Sample handling is critical for the assay. The blood should be drawn peripherally, kept at room temperature, and not sent through the pneumatic tube system.

Patients on aspirin, non-steroidal anti-inflammatory agents and other platelet inhibiting medications may show increased closure times. Patients with platelet counts below 150,000/uL or hematocrits below 30% may show increased closure times. Samples containing platelet clumps or hemolysis due to difficult blood draws may show increased closure times.

Reference: Dade Behring PFA-100 operations manual.




















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Created: JUly 18, 2002
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