Department of Laboratory Medicine
University of Washington
Clinical assay interference and limitations
von Willebrand Factor Antigen [VWFAG]
Methodology: Stago STA LIA vWF Antigen assay
The presence of rheumatoid factor may lead to an over-estimation of the vWF level. The extremely rare presence of anti-bovine albumin or anti-rabbit antibodies in certain subjects may lead to an over-estimation of vWF level. Like all antigenic tests, the vWF assay cannot detect the rare type 2 von Willebrand disease variants whose level of vWFAg is normal.
Reference: Stago STA Immuno-turbidometric vWF antigen assay package insert, 23327 Revised November 1997/3
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