CDC HIV Classification System - 1993

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1993 Revised Classification System for HIV Infection and the Expanded CDC Surveillance Case Definition of AIDS in Adults and Adolescents
Clinical Categories
CD4 T-cell Categories	A Asymptomatic	B Symptomatic	C AIDS Indicator Conditions
>500/mm3 (≥ 29%)	A1	B1	C1
200-499/mm3 (14-28%)	A2	B2	C2
<200/mm3 (<14%)	A3	B3	C3

(NOTE: Grey shading indicates definition of AIDS – CD4 < 200/mm3 (or <14%) OR Category C criteria listed below)

1993 CDC Surveillance Case Definition
Category A (Asymptomatic HIV)	Asymptomatic HIV Infection Persistent generalized lymphadenopathy (PGL) Acute HIV Infection with accompanying illness or hx of HIV infection
Category B (Symptomatic HIV)	- Bacillary angiomatosis - Candidiasis, oropharyngeal (thrush), vulvovaginal ( >1month) - Cervical dysplasia - Constitutional symptoms (fever >38 C or diarrhea >1 month) - Hairy Leukoplakia	- Herpes zoster (shingles) involving at least 2 distinct episodes or more than 1 dermatome - Idiopathic thrombocytopenia purpura - Listeriosis - Pelvic Inflammatory Disease - Peripheral Neuropathy
Category C (AIDS Defining Infections)	- Candidiasis of bronchi, trachea, or lungs - Candidiasis, esophageal - Cervical cancer, invasive - Coccidioidomycosis, disseminated or extrapulmonary - Cryptococcosis, extrapulmonary - Cryptosporidiosis, chronic (>1 month) - Cytomegalovirus disease or retinitis - Encephalopathy, HIV related - Herpes simplex virus (HSV) - Histoplasmosis, disseminated or extrapulmonary - HIV-associated dementia - Isosporiasis, chronic intestinal (>1 month) - Kaposi sarcoma	- Lymphoid interstitial pneumonia - Lymphoma, Burkitt’s, immunoblastic, primary of brain - Mycobacterium avium-intracellulare complex (MAC) - Mycobacterium tuberculosis, pulmonary or extrapulminary - Nocardiosis - Pneumocystis carinii pneumonia - Pneumonia, recurrent - Progressive multifocal leukoencephalopathy (PML) - Salmonella septicemia, recurrent - Toxoplasmosis of internal organs - Wasting syndrome due to HIV

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