Madison Clinic
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CDC HIV Classification System

 

2008


http://depts.washington.edu/hivaids/initial/case2/discussion.html

1993

1993 Revised Classification System for HIV Infection and the Expanded CDC Surveillance Case Definition of AIDS in Adults and Adolescents

Clinical Categories


CD4 T-cell Categories

A

Asymptomatic

B

Symptomatic

C

AIDS Indicator Conditions

>500/mm3 (≥ 29%)
A1
B1
C1
200-499/mm3 (14-28%)
A2
B2
C2
<200/mm3 (<14%)
A3
B3
C3

(NOTE: Grey shading indicates definition of AIDS – CD4 < 200/mm3 (or <14%) OR Category C criteria listed below)

1993 CDC Surveillance Case Definition
Category A
(Asymptomatic HIV)
Asymptomatic HIV Infection
Persistent generalized lymphadenopathy (PGL)
Acute HIV Infection with accompanying illness or hx of HIV infection

Category B
(Symptomatic HIV)

- Bacillary angiomatosis
- Candidiasis, oropharyngeal (thrush), vulvovaginal ( >1month)
- Cervical dysplasia
- Constitutional symptoms (fever >38 C or diarrhea >1 month)
- Hairy Leukoplakia

- Herpes zoster (shingles) involving at least 2 distinct episodes or more than 1 dermatome
- Idiopathic thrombocytopenia purpura
- Listeriosis
- Pelvic Inflammatory Disease
- Peripheral Neuropathy

Category C
(AIDS Defining Infections)

- Candidiasis of bronchi, trachea, or lungs
- Candidiasis, esophageal
- Cervical cancer, invasive
- Coccidioidomycosis, disseminated or extrapulmonary
- Cryptococcosis, extrapulmonary
- Cryptosporidiosis, chronic (>1 month)
- Cytomegalovirus disease or retinitis
- Encephalopathy, HIV related
- Herpes simplex virus (HSV)
- Histoplasmosis, disseminated or extrapulmonary
- HIV-associated dementia
- Isosporiasis, chronic intestinal (>1 month)
- Kaposi sarcoma

- Lymphoid interstitial pneumonia
- Lymphoma, Burkitt’s, immunoblastic, primary of brain
- Mycobacterium avium-intracellulare complex (MAC)
- Mycobacterium tuberculosis, pulmonary or extrapulminary
- Nocardiosis
- Pneumocystis carinii pneumonia
- Pneumonia, recurrent
- Progressive multifocal leukoencephalopathy (PML)
- Salmonella septicemia, recurrent
- Toxoplasmosis of internal organs
- Wasting syndrome due to HIV

 

 

 

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