Madison Clinic
For Providers For Patients Pharmacy Calendar Resources

Post Expsoure Prophylaxis - Lab Monitoring

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Note: For management of specific exposures please see the PEP sections for “Occupational” and “Non-occupational” exposures in the Guideline section. For more details about the PEP protocol, please see the “PEP protocol” in the protocol section.

I. Occupational Exposures

a) Non-HMC Employee Occupational Exposures:

 

Baseline

2 weeks

6 weeks

12 weeks

24 weeks

All patients

CBC, CMP, HBV, HCV, HIV

 

HBV*, HCV*,
HIV

HCV*, HIV

HCV*, HIV

Women

b -HCG

 

 

 

 

On ARVs

 

CBC, CMP

 

 

 

If source HCV+ or high risk

 

 

HCV RNA, ALT

 

 

* If source is known to be HBV or HCV negative, follow-up HBV and/or HCV serologies need not be drawn.

b) HMC-Employee Occupational Exposures**:

 
Baseline
2 weeks
6 weeks
12 weeks
24 weeks

All Patients on ARVs

 

CBC, CMP

 

 

 

** All HMC employees should receive the identical lab monitoring as non-HMC employees, but the lab testing other than the 2 weeks toxicity labs will be drawn through employee health (or the ER).

II. Non-occupational Exposures

a) Sexual Exposures:

 

Baseline

2 weeks

6 weeks

12 weeks

24 weeks

All patients

CBC, CMP, HIV, HBV, HCV, RPR, GC/CT (oral (GC only), rectal, and/or urethral depending on exposure)

 

HIV, RPR

HIV

HIV

Women

b -HCG

 

 

 

 

On ARVs

 

CBC, CMP

 

 

 

b) Needle Exposures:

Baseline

2 weeks

6 weeks

12 weeks

24 weeks

All patients

CBC, CMP, HIV, HBV, HCV

 

HCV***, HIV

HCV***, HIV

HCV***, HIV

Women

b -HCG

 

 

 

 

On ARVs

 

CBC, CMP

 

 

 

If source HCV+ or high risk

 

 

HCV RNA, ALT

 

 

*** If source is known to be HCV negative, HCV antibody does not need to be drawn during follow-up.

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