Pilot Project Awards

The UW ADRC seeks proposals for pilot projects that use its resources to advance the understanding, diagnosis, and/or treatment of Alzheimer’s disease. The UW ADRC will fund at least two awards for junior researchers of up $30,000 each, and one award of up to $75,000, which is also open to established researchers new to the ADRC.


The ADRC Request for Proposals for the 2019 - 2020 funding period is now available. the UW ADRC has awarded funds to junior faculty and established researchers new to the ADRC. Funds will be awarded for a one year project period, 5/1/2018 through 4/30/2019. The proposed project must be feasible in this time frame.

2019-2020

Please see the ADRC Request for Proposals

2018-2019

Serum amyloid A as a liver-derived mediator of Alzheimer’s disease. Michelle Erickson, PhD, Research Assistant Professor, UW Gerontology and Geriatric Medicine / Research Biologist, VA Puget Sound Healthcare System 

Contribution of human-specific repeat expansions to Alzheimer’s Disease. Paul Valdmanis, PhD, Assistant Professor, Division of Medical Genetics, UW  

Development of Ultrafast Resting-State fMRI as a Biomarker for Alzheimer’s Disease. Hesamoddin Jahanian, PhD, Assistant Professor, Integrated Brain Imaging Center (IBIC), Department of Radiology, UW

Epigenetic role for histone deacetylase 2 in Alzheimer’s disease pathogenesis. Richard S. Morrison, PhD, Staatz Professor of Neurological Surgery, UW; Director, Center for Neuroproteomics 

Neurodegeneration by adipocyte-derived exosomes in dementia. Robert Freishtat, MD, MPH, Chief of Emergency Medicine, Children’s National Health System/ Professor of Pediatrics, Emergency Medicine, and Integrative Systems Biology, George Washington University School of Medicine and Health Sciences

2016-2017

Multiplex assay for the quantification of antigens in paraffin-embedded tissue. Martin Darvas, PhD

Probing the role of endocytic network in sporadic AD risk using human induced pluripotent stem cells. Jessica Young, PhD

Alzheimer’s disease research pilot for American Indians and Alaska natives. Meghan Jernigan, MPH

Dopaminergic influence on amyloid beta. Erica Melief, PhD

Human and Non-Human Primate Synaptic Damage. Caitlin Latimer, MD, PhD

 

Previously Funded Pilot Projects

The effects of natural variation on Alzheimer's pathology in Drosophila. Adrienne Wang, PhD

Novel Data and Tissue Resource to Study CTE and AD Neuropathology. Desiree Marshall, MD

Epigenetics of APOE in Alzheimer’s Disease Neurons. Jessica (Foraker) Tulloch, PhD

Health Education, Aerobic and Resistance Training (HEART) in Prediabetic African Americans to compare the effects of exercise and health education on the thinking abilities, insulin sensitivity, and levels of Alzheimer's biomarkers in a group of African Americans with prediabetes. Jeannine Skinner, PhD

Quantification of A-beta and Tau in CSF by LC-MS/MS. Andrew Hoofnagle, MD, PhD

Preclinical Study of D2 Antagonists for Neuroprotection Against Pathological Tau. Brian Kraemer, MD, PhD

Neuroimaging Biomakers of Cognitive Resilience Among APOE-4 Carriers. Tara Madhyastha, PhD

Role of the R41H TREM2 variant in the pathogenesis of late onset AD. Olena Korvatska, PhD

Pilot study of potential Alzheimer’s disease biomarkers in human saliva. Min Shi, PhD

Strong Heart Stroke Study for Urban Indians and Alaska Natives Americans. Lonnie Nelson, PhD

Seed Grant Projects

Cell autonomous and cell non autonomous pathologies caused by expression of A-beta, Tau and alpha-synuclein in C. elegans. Alexander Mendenhall, PhD

Neuropathology Core resource for induced pluripotent stem cells. C. Dirk Keene, MD, PhD