The Dynamic Chromosome

Course web page:  http://libguides.fhcrc.org/conj533

Location:  FHCRC B1-072

Class size: 30 students, with preference given to MCB students

Course description: This course is a graduate level introduction to the chromosome, viewing it as the ultimate organelle. Topics this year will focus on the functions and evolution of chromosomal elements as well as the mechanisms that ensure the maintenance and propagation of chromosomes. The class will use a combination of lecture, literature review, and in-class discussion to explore genetic, biochemical, and cytological methods for defining our current knowledge about chromosomes. The course requires students to have taken undergraduate cell biology, biochemistry and genetics. Active participation in discussion is required

Learning objectives: Students should have a good understanding of the basic biology of the chromosome.  The will also become familiar with both the classic and current experimental techniques used to study various aspects of chromosome biology. 

Prerequisites:  Students must have a basic understanding of molecular biology and basic techniques (ie:  they should know what an immunoprecipitation is and what DNA is)

Course materials and/or textbooks: The course material will be composed of original literature that will be assigned each class.

Course requirements, examinations and grading: There will be four problem sets and a class participation grade.

Sample Syllabus: