Technologies for Genome Analysis

Course Number: 
GENOME 552
Course Type: 
Methods
Currently Offered: 
Yes
Credits: 
1.5
Quarter: 
Autumn
Weeks: 
6-10
Meeting Time: 
T Th 1030-1150
Location: 
UW
Instructor (non-MCB Faculty): 
Nickerson, Debbie
Class Size: 
Permission of the instructor
Course Description: 

Discussion of current and newly-emerging technologies in genome analysis with regard to applications in biology and medicine and to potential advantages and limitations.

Learning Objectives: 

To introduce students to the past, present and future of emerging technologies for genome analysis related to large-scale sequencing, parallel capture and analysis, genetic and biological analysis.

Course requirements, examinations and grading: 

Grades will be based on the average of all the exercises assigned during this course (85%) and your presentations and participation in class discussions (15%).  Participation in class discussions is essential.

Sample Schedule:

Week Tues Thurs
  1 Overview of Genome Analysis – The Human Genome Genomics—A Changing Tide!
  2 Detection key to new technologies Massively parallel arrays preceded massively parallel sequencing 
  3 Next-Generation Sequencing Technologies Single Nucleotide and Structural Variation
  4 Genetic Association Mapping Large-Scale On-Going Projects—large-scale sequencing of complex traits and ENCODE
  5 Next-Generation—Large-Scale Biology  
Areas of Interest: 
Cancer Biology
Areas of Interest: 
Genetics, Genomics & Evolution
Methods Area: 
Cancer Biology
Cell Signaling & Cell/Environment Interactions
Gene Expression, Cell Cycle & Chromosome Biology
Genetics, Genomics & Evolution
Microbiology, Infection & Immunity
Molecular Structure & Computational Biology