Embryos, Genes & Development
This course introduces vertebrate and invertebrate development, emphasizing cellular, genetic and molecular mechanisms. The course will focus on development of the model organisms zebra fish, fruit flies, and nematodes. Emphasis will be on understanding fundamental embryological processes such as induction, determination, and pattern formation. Current technologies available for each system will be described, such as the construction of transgenic animals, genetics, mosaic analysis, homologous recombination, and classical embryonic manipulations. Selected topics include developmental genetics of regulatory hierarchies, lateral inhibition, and cell lineage analysis. Following introductory lectures, the course will focus on primary literature detailing the current state of the field using journal club presentations (by students).
MCB Faculty Instructors: Jim Priess, Cecilia Moens, Susan Parkhurst