Biochemistry and Genetics of Pathogens and Their Hosts

Course Number: 
PABIO 551
Course Type: 
Elective
Currently Offered: 
No
Credits: 
4
Quarter: 
Autumn
Meeting Time: 
MW 330-520
Location: 
UW
Instructor (MCB Faculty): 
Campbell, Lee
Instructor (MCB Faculty): 
Rajagopal, Lakshmi
Course Description: 

This course has been developed for students who need a solid foundation in the application of biochemistry, molecular biology and genetics as they relate to host/pathogen relationships and to human disease. Topics include genome structure, gene expression, and protein structure/function/biosynthesis, with emphasis on their role in specific diseases.Technological advances and molecular techniques will be discussed, with emphasis on their relationship to the study of disease processes.

Learning Objectives: 

Prerequisites: 
Students should have an understanding of basic biology and molecular biology techniques. Undergraduate biochemistry, genetics and molecular biology are strongly recommended.
Course requirements, examinations and grading: 
The course grade will consist of the following:
  • Problems sets 20%
  • Midterm 30% 
  • Final 30% 
  • Class participation 20% (not just attendance)

Course web site: http://staff.washington.edu/lgoo/PABIO551.shtml

Sample Schedule:

Week Mon Weds
  1 Introduction Genetics
  2 DNA detection/methods DNA replication/repair
  3 RNA genomes RNA processing
  4 DNA recombination Functional RNAs
  5 Transcription in prokaryotes Transcription in eukaryotes
  6 Protein structure Translation
  7 Techniques to study proteins Enzymology
  8 Fueling cellular processes Cellular nutrition
  9 Lipids Carbohydrates
Areas of Interest: 
Microbiology, Infection & Immunity
Elective Area: 
Microbiology, Infection & Immunity
Molecular Structure & Computational Biology