Ion Channel Pharmacology

Course Number: 
PHCOL 529
Course Type: 
Elective
Currently Offered: 
Yes
Credits: 
2
Quarter: 
Autumn
Location: 
UW
Instructor (MCB Faculty): 
Catterall, William
Instructor (MCB Faculty): 
Tempel, Bruce
Course Description: 

Current topics in ion channel structure, function, genetics, and pharmacology, including consideration of role in electrical signaling in cell membranes and information transfer and processing in nervous system, inherited diseases of ion channels, and sites and mechanisms of action of drugs and toxins.

Course Web Site: http://courses.washington.edu/phcol529/index.shtml

Sample Schedule:

 

Week Topic
  1 Intro to Na and Ca Channels
  2 Intro to K Channels
  3 K Channels in Epilepsy
  4 Na Channels in Periodic Paralysis, Long QT Syndrome and Epilepsy
  5 Ca Channels in Periodic Paralysis, Migraine, and Ataxia
  6 CRAC, Orai, and SCID in Lymphocytes
  7 TRP Channels in Thermodetection and Mechanotransduction
  8 Seminar
  9 Chloride Channels in Myotonia and Dent's Disease
 10 Ion Pumps, Structure and Disease
 
Areas of Interest: 
Neuroscience
Elective Area: 
Neuroscience