Biggins, Sue

Faculty Profile

First Name: 
Sue
Last Name: 
Biggins
[field_fname-formatted] [field_lname-formatted]
Title: 
Member
Primary Institution: 
FHCRC
Department/Division: 
Basic Sciences
Department/Division: 
other
E-Mail: 
Mail/Box #: 

A2-168

Office Location: 

A2-155

Office Phone: 
(206) 667-1351
Alternate Phone: 
(206) 667-5766
Research

Research Summary: 

How do cells faithfully inherit a complete set of chromosomes during every cell division? We are studying the mechanisms that govern chromosome segregation during the cell cycle. Our focus is on the kinetochore, the protein complex that binds to microtubules. We study the regulation of kinetochore assembly and function, and the mechanisms that establish the specialized chromatin structure at centromeres. Recently, we have developed two ways to purify kinetochores and are now conducting biophysical and structural studies to complement the genetics and cell biology in the lab.

Short Research Description: 
Regulation of Chromosome Segregation
Areas of Interest: 
Gene Expression, Cell Cycle & Chromosome Biology
Keywords: 
<p> Cell Biology, Genetics, Mitosis, Cell Cycle, Chromosomes, Genetics, Kinetochores, Yeast, Aurora kinase</p>
Publications


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