andrewms

Faculty Profile

First Name: 
Andrew
Last Name: 
Scharenberg
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Immunology
Mail/Box #: 

Box 359300-C9S-6

Office Location: 

Seattle Children's Research Institute
1900 9th Ave.
Box 359300-C9S-6
Seattle, WA 98101

Office Phone: 
(206) 987-7314
Research

Research Summary: 

The Scharenberg laboratory is interested in signal transduction mechanisms and cation channel function in the immune system, and engineering of homing endonucleases for gene repair applications in inherited immune deficiencies. Current effort is centered in two areas:

1) Signal transduction in immune cells, particularly signaling pathways affected in primary immune deficiencies and those involving ion channels.

2) Use of homing endonucleases in targeted gene repair of genes responsible for primary immune deficiencies. A new approach to gene therapy involves targeted repair of a gene via the induction of a double strand break at or near the mutation site.

Short Research Description: 
gene repair applications in inherited immune deficiencies
Areas of Interest: 
Cell Signaling & Cell/Environment Interactions
Keywords: 
<p> Immunology, Ion Channels, Signal Transduction</p>
Publications

Taking Students
Year: 
2011 - 2012

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