The defining feature of eukaryotic cells is the presence of numerous organelles. Defined by their membrane composition, each provides the optimal environment for specific cellular processes. The precise lipid and protein composition of organelle membranes, and the formation of sub-domains within them, are essential to all cellular processes.
The Bajjalieh Lab studies how the assembly of protein-lipid complexes is regulated with emphasis on the presynaptic terminal of neurons. To do this we are developing several new techniques to track transient events in cells. The work is releavant to understanding normal nervous system functioning as well as neurological disorders such as epilepsy and Huntington's disease.
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Fred Hutch | University of Washington
Institute for Systems Biology (ISB)| Center for Infectious Disease Research