Asbury, Charles

Faculty Profile

First Name: 
Charles
Last Name: 
Asbury
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Title: 
Associate Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Physiology & Biophysics
Mail/Box #: 

357290

Office Location: 

G225A, Health Sciences Building

Office Phone: 
(206) 543-7808
Alternate Phone: 
(206) 543-6968
Research

Research Summary: 

Our laboratory studies the mitotic spindle, an exquisite molecular machine that organizes and separates duplicated chromosomes during cell division, thereby ensuring equal partitioning of the genetic material. To uncover how this machine operates, we reconstitute spindle functions using pure components and apply advanced biophysical tools for manipulating and tracking individual molecules, such as laser trapping and ultrasensitive fluorescence microscopy.

Short Research Description: 
Molecular biomechanics of mitosis and the cytoskeleton
Areas of Interest: 
Cancer Biology
Cell Signaling & Cell/Environment Interactions
Gene Expression, Cell Cycle & Chromosome Biology
Molecular Structure & Computational Biology
Keywords: 
<p> kinetochores, mitosis, chromosome movement, microtubules, optical trapping, optical tweezers, laser tweezers, single molecule biophysics, kinesin, molecular motors, cell motility</p>
Publications


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