Miller, Dana

Faculty Profile

First Name: 
Dana
Last Name: 
Miller
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Title: 
Assistant Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Biochemistry
E-Mail: 
Mail/Box #: 

357350

Office Location: 

J-591 Health Sciences Building

Office Phone: 
206-685-5025
Research

Research Summary: 

We are interested in learning how animals survive in a world where environmental conditions are constantly changing. Our focus is on the effets of small gasses, like oxygen (O2) and hydrogen sulfide (H2S). We use C. elegans to discover fundamental aspects of cellular physiology and homeostasis in animals. Some questions that we are currently interested in: 

  • What determines the epigenetic effects of H2S, and what can we learn about the long-term effects of environmental exposures? 
  • What goes wrong when cells don't get enough O2?
  • How does suspended animation allow cells maintain homeostasis and survive?
  • How do different tissues communicate when animals are exposed to stressful environments?
  • What are the genetic pathways that control responses to H2S?
  • How do H2S and O2 signaling pathways interact to modulate survival and lifespan?
  • Can we devise new strategies to improve survival of stroke, traumatic injury, neurodegeneration, and related insults?
Short Research Description: 
Responses to hydrogen sulfide and hypoxia
Areas of Interest: 
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Gene Expression, Cell Cycle & Chromosome Biology
Genetics, Genomics & Evolution
Keywords: 
<p> hypoxia, oxygen, diapause, hydrogen sulfide, aging, lifespan, polyglutamine, neurodegenerative disease, C. elegans, suspended animation</p>
Publications


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