Rawlings, David

Faculty Profile

First Name: 
David
Last Name: 
Rawlings
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Immunology
Mail/Box #: 

Box 359300

Office Location: 

Seattle Children's Hospital Research Institute
1900 Ninth Ave.
Box 359300-C9S
Seattle, WA 98195-9300

Office Phone: 
(206) 987-7450
Alternate Phone: 
(206) 987-7319
Research

Research Summary: 

Dr. Rawlings’ primary research interests include dysregulated B cell development and signaling leading to immunodeficiency, autoimmunity or lymphoid malignancies, and the development of gene therapy and gene editing for immune system diseases. His laboratory uses expertise in basic and clinical immunology, signal transduction and lymphocyte developmental biology to understand how altered signals can lead to immunologic disease, with the ultimate goal of developing translational therapies capable of specifically modulating these disorders. Dr. Rawlings is a member of multiple regional and national organizations, an NIH study section member, and ad hoc reviewer for various grant programs and immunology journals. He also co-directs the Northwest Genome Engineering Consortium, a research program funded as part of the NIH Roadmap for Medical Research and comprised of seven collaborative projects focused on developing nucleases and delivery systems for targeted gene editing in hematopoietic stem cells.

Short Research Description: 
dysregulated B cell development and signaling, gene therapy
Areas of Interest: 
Microbiology, Infection & Immunity
Keywords: 
<p> B cells, T cells, lymphocyte development, signal transduction, immunodeficiency, gene therapy, leukemia, lymphoma, autoimmunity</p>
Publications


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