The inherent contradiction of a toxic gas that can elicit beneficial effects sparked my interest in the genetic mechanisms behind an organism’s response to hydrogen sulfide (H2S). I am especially interested in understanding the intricacies behind the dose and time dependent response to H2S on a molecular level.
When C. elegans are exposed to sub-lethal levels of H2S during development, they are able to survive otherwise lethal concentrations later in life. My current research interests are focused on understanding the genetic response and pathways behind this “remembered” adaptation to H2S.
Copyright © 2003-2014 Molecular & Cellular Biology Program, University of Washington
Fred Hutch | University of Washington
Institute for Systems Biology (ISB)| Center for Infectious Disease Research