elbo@u.washington.edu
Box 355065
Foege S-103B
http://elbo.gs.washington.edu/
Borenstein’s lab focuses on computational research in Evolutionary Systems Biology - an emerging field that examines the interplay between the evolutionary process and the organization of complex biological systems, with an eye to expanding fundamental theories in evolutionary dynamics, systems biology, and ecology. Specific research themes include: 1. Large scale computational analysis of complex biological networks and their evolution (with an emphasis on metabolic networks). 2. Metabolic interactions, community structure and systems biology of microbial communities (and specifically the human microbiome) and analysis of metagenomic data. 3. Modularity, robustness, evolvability, and assembly rules of biological systems. 4. Theory of systems biology , population genetics, and evolutionary theory. Research in the lab is multidisciplinary in nature and spans several levels of abstraction, ranging from state of the art computational analysis of complex networks and high-throughput data to theoretical studies of mathematical and computational models.