Malik, Harmit

Faculty Profile

Submitted by Malik, Harmit on Fri, 10/08/2010 - 6:24pm

First Name:

Harmit

Last Name:

Malik

Title:

Member

Primary Institution:

FHCRC

Department/Division:

Basic Sciences

Department/Division:

other

E-Mail:

hsmalik@fhcrc.org

Mail/Box #:

A2-025

Office Location:

Fred Hutchinson Cancer Research Center
1100 Fairview Avenue N, A2-205
Mailstop A2-025
Seattle WA 98109.

Office Phone:

(206) 667-5204

Lab Website:

http://www.fhcrc.org/science/labs/malik/

Research

Research Summary:

Our genomes are a tenuous conglomerate of different genetic entities, each trying to maximize their own evolutionary success, often at great cost to their genomic neighbors. As expected, this conflict can create problems for the host organism. My lab is interested in evolutionary studies of genetic conflict to gain insight into their mechanisms and consequences. We study genetic conflicts primarily in three systems: Drosophila, primates and yeast. While there are a number of investigative projects that are going on at any given time in the lab, our focus is on three conflicts in particular:

* centromeres

* innate and intrinsic immunity against viruses in primates

* mobile genetic elements in Drosophila.

Short Research Description:

evolutionary studies of genetic conflict

Areas of Interest:

Gene Expression, Cell Cycle & Chromosome Biology

Genetics, Genomics & Evolution

Microbiology, Infection & Immunity

Keywords:

<p> Mobile genetic elements, rapidly evolving proteins in yeast and Drosophila, Phylogenomics, sequence analysis, evolution, speciation, satellite DNA, centromeres</p>

Publications

PubMed Search Term:

Malik HS

Taking Students

Year:

2012

Search

Malik, Harmit

Faculty Profile

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