Chamberlain, Jeffrey

Faculty Profile

First Name: 
Jeffrey
Last Name: 
Chamberlain
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Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Biochemistry
E-Mail: 
Mail/Box #: 

357720

Office Location: 

K243b HSB

Office Phone: 
(206) 616-6645
Alternate Phone: 
(206) 221-5363
Research

Research Summary: 

The Chamberlain laboratory is focused on understanding and developing treatments for the muscular dystrophies. A major area of interest involves the development of gene and stem cell therapies for the muscular dystrophies. The lab is also interested in understanding the function of dystrophin, the protein missing in the most common form of muscular dystrophy, and how the protein complex that associates with dystrophin is assembled and regulated. Our lab has shown that new genes can be delivered throughout the body of mouse models for muscular dystrophy, leading to a major improvement in muscle strength and extending lifespan. These approaches are being developed for future clinical trials. We are also studying different types of muscle stem cells that may be of use for cell-based therapies.

Short Research Description: 
Genetics and therapies of muscular dystrophy
Areas of Interest: 
Developmental Biology, Stem Cells & Aging
Genetics, Genomics & Evolution
Neuroscience
Keywords: 
<p> Gene Therapy, Muscular Dystrophy, Stem cells, genetic disease, virus, genetics, aging</p>
Publications

Taking Students
Year: 
2013 - 2014

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