Klevit, Rachel

Faculty Profile

First Name: 
Rachel
Last Name: 
Klevit
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Biochemistry
Mail/Box #: 

357350

Office Location: 

K466 HSB

Office Phone: 
(206) 543-5891
Research

Research Summary: 

Research in the Klevit group is directed towards an understanding of molecular recognition, with an emphasis on protein-protein interactions that play important roles in human disease. We use a variety of structural, biochemical, molecular biological, and biophysical techniques, with a major emphasis on high resolution NMR spectroscopy and mass spectrometry. Furthermore, we collaborate with colleagues focused on functional aspects of the systems we study. Ongoing projects in the group include the following systems: BRCA1, the breast cancer susceptibility protein; protein ubiquitination in general; human small heat shock proteins alpha-B crystallin and HSP27; and PhoQ, a virulence factor in pathogenic bacteria.

Short Research Description: 
Structural Biology in Human Health & Disease
Areas of Interest: 
Molecular Structure & Computational Biology
Keywords: 
<p> BRCA1, breast cancer proteins, ubiquitination, small heat shock proteins, biochemistry, proteins, protein structure, protein structure/function, biology, molecular, chemical sciences, molecular recognition, protein-protein interactions, spectroscopy, molecular structure, nmr, mass spectrometry</p>
Publications


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