1600 S. Columbian Way, S 182Seattle, WA 98108
We work to understand the molecular mechanisms driving neurodegeneration in Alzheimer’s disease, amyotrophic lateral sclerosis and other aging related disorders. One feature common to aging related neurodegenerative diseases is abnormal aggregation of specific proteins. We use a variety of model systems including C. elegans, cultured human cells, mice, and human tissue to explore neuroprotective strategies against protein aggregation. Our focus is on identifying genetic pathways and small molecules preventing protein aggregation and the resulting neurotoxicity.
Copyright © 2003-2014 Molecular & Cellular Biology Program, University of Washington
Fred Hutch | University of Washington
Institute for Systems Biology (ISB)| Center for Infectious Disease Research