Laflamme, Michael

Faculty Profile

First Name: 
Michael
Last Name: 
Laflamme
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Title: 
Associate Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Pathology
Mail/Box #: 

358050

Office Location: 

Rm # 442 Brotman Building, 815 Mercer St., South Lake Union campus

Office Phone: 
(206) 897-1518
Alternate Phone: 
(206) 897-1519
Research

Research Summary: 

Our lab is broadly interested in the use of stem cells for cardiac repair, but with a particular emphasis on electrophysiological issues related to cardiomyocytes derived from human pluripotent stem cells (hPSCs). We have ongoing research on topics including 1) elucidating the pathways controlling cardiac subtype specification (e.g. nodal versus ventricular differentiation) in hPSC-derived cultures, 2) methods to promote the functional maturation of hPSC-derived ventricular myocytes, 3) enhancing the electromechanical integration of hPSC-derived grafts in injured hearts, and 4) determining the electrocardiographic consequences of cell transplantation on the recipient

Short Research Description: 
Electrophysiological properties of ESC-derived cardiomyocyte
Areas of Interest: 
Cell Signaling & Cell/Environment Interactions
Developmental Biology, Stem Cells & Aging
Keywords: 
<p> stem cell, human embryonic stem cell, heart, cardiac, cardiomyocyte, electrophysiology, ion channel, differentiation, muscle, patch clamp, differentiation, developmental biology, cell therapy, pathology, cardiovascular</p>
Publications


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