The Berg lab studies the formation of tubes, using the dorsal appendages (DAs) of Drosophila melanogaster eggs as a model. The DAs are two eggshell structures formed at the dorsal anterior of the egg; they are secreted by epithelial tubes that form a mould. These tubes form from a flat sheet of follicle cells surrounding the oocyte. The sheet forms two tubes in a manner similar to neural tube formation in vertebrates, and the small tubes then elongate migrate anteriorly. My project endeavors to discover what signaling molecules are imortant for giding these tubes in their migration.
Copyright © 2003-2013 Molecular & Cellular Biology Program, University of Washington
Fred Hutchison Cancer Research Center | University of Washington
Institute for Systems Biology | Seattle Biomed