J-357 Health Sciences Bldg
We seek to understand how the endolysosomal membrane system of eukaryotic cells is "wired" -- how it is organized, how it is regulated, and how its regulation is integrated with cellular metabolism.
We work at levels ranging from the whole organism to single molecules, and use yeast genetics, biochemistry, in vitro reconstitution, quantitative optical microscopy, fluorescence spectroscopy, electron microscopy, and electrophysiology. Our favorite model systems are budding yeast (S. cerevisiae) and nematode worm (C. elegans), but projects with other systems are possible. We emphasize the development of new assays and probes that allow us to explore new aspects of cell biology.
Current projects include:
Our work is currently funded by the NIH and the American Cancer Society.
Copyright © 2003-2014 Molecular & Cellular Biology Program, University of Washington
Fred Hutchison Cancer Research Center | University of Washington
Institute for Systems Biology | Seattle Biomed