850 Republican St., Brotman Bldg. Rm. 453
Our lab studies stem cell biology of the cardiovascular system. Our basic research efforts focus on mechanisms controlling cardiovascular differentiation from pluripotent human stem cells (hESCs and hiPSCs). We work collaboratively with groups studying developmental systems like zebrafish to validate new molecules and pathways that are identified in our stem cell systems. Our translational efforts strive to develop therapies that will regenerate the heart after injury, e.g. myocardial infarction (heart attack). These include cell transplantation and tissue engineering. Most recently, we have established a program using hiPSCs to model genetically based heart disease in a dish, with a focus on hypertrophic cardiomyopathy.
Copyright © 2003-2013 Molecular & Cellular Biology Program, University of Washington
Fred Hutchison Cancer Research Center | University of Washington
Institute for Systems Biology | Seattle Biomed