Murry, Charles

Faculty Profile

First Name: 
Charles
Last Name: 
Murry
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Pathology
Mail/Box #: 

358050

Office Location: 

850 Republican St., Brotman Bldg. Rm. 453

Office Phone: 
(206) 616-8685
Research

Research Summary: 

Our lab studies stem cell biology of the cardiovascular system.  Our basic research efforts focus on mechanisms controlling cardiovascular differentiation from pluripotent human stem cells (hESCs and hiPSCs).  We work collaboratively with groups studying developmental systems like zebrafish to validate new molecules and pathways that are identified in our stem cell systems.  Our translational efforts strive to develop therapies that will regenerate the heart after injury, e.g. myocardial infarction (heart attack).  These include cell transplantation and tissue engineering.  Most recently, we have established a program using hiPSCs to model genetically based heart disease in a dish, with a focus on hypertrophic cardiomyopathy.

Short Research Description: 
Stem cell biology of the cardiovascular system
Areas of Interest: 
Developmental Biology, Stem Cells & Aging
Keywords: 
<p> heart, myocardium, infarction, embryonic stem cells, ES cells, ESCs, induced pluripotent stem cells, iPSCs, iPS cells, adult stem cells, regeneration, tissue engineering, wound healing, remodeling, angiogenesis, gene therapy, development, differentiation, growth factors, mouse models of disease</p>
Publications


Related content

Student Profile