Oshima, Junko

Faculty Profile

Submitted by Oshima, Junko on Fri, 10/08/2010 - 6:24pm

First Name:

Junko

Last Name:

Oshima

Title:

Research Associate Professor

Primary Institution:

Department/Division:

other

Department/Division:

Pathology

E-Mail:

picard@u.washington.edu

Mail/Box #:

357470

Office Location:

K543B

Office Phone:

(206) 685-2719

Alternate Phone:

(206) 543-5088

Lab Website:

http://www.wernersyndrome.org/

Research

Research Summary:

Our laboratory is studying the genetic mechanisms of aging, with a special interest in the process of accelerated aging (progeroid syndromes). In the past, we identified two classes of genes that are responsible for the progeroid syndromes; a DNA repair protein (WRN helicase) and nuclear structural proteins (lamins). Current research projects include (1) molecular and cellular mechanisms of accelerated aging involving telomere, lamin and the WRN helicase; and (2) identification of new progeroid syndrome genes. Other ongoing studies include the patient registry of Werner syndrome (“Progeria of Adult”) and genetic risk factors of common age-related disorders.

Short Research Description:

Human Aging and Progeroid Syndromes

Areas of Interest:

Cancer Biology

Genetics, Genomics & Evolution

Keywords:

<p> Biotechnology, Cardiovascular Biology, Cardiovascular Physiology, Gene Expression, Gene Regulation, Gerontology, Medical Genetics, Pathology</p>

Publications

PubMed Search Term:

oshima j seattle