Promislow, Daniel

Faculty Profile

First Name: 
Daniel
Last Name: 
Promislow
[field_fname-formatted] [field_lname-formatted]
Title: 
Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Pathology
E-Mail: 
Mail/Box #: 

357705

Office Location: 

K-078 HSB

Office Phone: 
206-616-6994
Research

Research Summary: 

My lab studies natural genetic variation of aging and reproduction. Most of our research is focused on the fruit fly, but we also have ongoing studies on aging in marmosets and dogs. We use a diversity of approaches in our lab, including molecular and quantitative genetics, evolutionary theory, and systems biology methods to construct and analyze genetic and metabolomic networks. Among the current projects in the lab are 1) a study on the role that insulin signaling plays in determining how age affects mate attractiveness and mate preference; 2) the use of metabolomic profiling to identify novel aging-associated pathways; 3) identification of natural genetic modifiers of neurodegenerative disease in Drosophila; 4) studies on the molecular basis of sex differences in longevity; and 5) developing the fly as a model for pharmacogenomic studies.

Short Research Description: 
Aging, networks and genetic variation in Drosophila
Areas of Interest: 
Developmental Biology, Stem Cells & Aging
Genetics, Genomics & Evolution
Keywords: 
<p> Drosophila, aging, senescence, networks, metabolomics, sexual selection, evolution, dogs, quantitative genetics, demography</p>
Publications

Taking Students
Year: 
2014 - 2019