Queitsch, Christine

Faculty Profile

First Name: 
Christine
Last Name: 
Queitsch
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Title: 
Assistant Professor
Primary Institution: 
UW
Department/Division: 
other
Department/Division: 
Genome Sciences
Mail/Box #: 

Box 355065

Office Location: 

Foege Building, Room S-410A

Office Phone: 
(206) 685-8935
Research

Research Summary: 

Wild-type phenotypes are remarkably robust to environmental and genetic variation, yet evolutionary novelty continues to arise. What are the molecular underpinnings of phenotypic robustness? How do novel shapes and functions evolve from a robust wild-type phenotype? Natural selection draws upon phenotypic variation among individuals. Although selection can only fix traits with an underlying genetic basis, phenotypic variance results from a complex interplay of genetic, epigenetic, and environmental factors. We seek to identify and understand molecular mechanisms that have the potential to rapidly generate selectable phenotypic variation. Currently, we focus on Hsp90-mediated genetic capacitance and the phenotypic consequences of length variability polymorphisms in conserved tandem repeats.

Short Research Description: 
phenotypic robustness and evolvability
Areas of Interest: 
Cell Signaling & Cell/Environment Interactions
Genetics, Genomics & Evolution
Keywords: 
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Publications


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